Improving CPAP use in adults with severe sleep apnea through motivation and psychological factors

Impact of Phenotypic and Psychological Characteristics and a Motivational Telephone Intervention on Continuous Positive Airway Pressure (CPAP) Adherence in Patients With Severe Obstructive Sleep Apnea

Not applicable Interventional University of Split, School of Medicine · NCT06994247

This study is testing if a motivational phone call can help adults with severe sleep apnea stick to their CPAP therapy better than those who don’t get the call.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Split, School of Medicine Academic / other
Locations1 site (Split, Dalmatia)
Trial IDNCT06994247 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to investigate the relationship between psychological traits and adherence to CPAP therapy in adults diagnosed with severe obstructive sleep apnea. Participants will complete questionnaires assessing their psychological characteristics and self-efficacy before starting CPAP therapy. Additionally, the study will evaluate the effectiveness of a motivational phone call made one month after therapy initiation in enhancing adherence to CPAP use at the three-month follow-up. The trial will compare adherence rates between those who receive the motivational call and those who do not.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a diagnosis of severe obstructive sleep apnea who are starting CPAP therapy.

Not a fit: Patients with central sleep apnea, significant comorbidities, or those who have previously used CPAP therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved adherence to CPAP therapy, enhancing treatment outcomes for patients with severe sleep apnea.

How similar studies have performed: While the specific approach of combining psychological assessment with motivational intervention is novel, similar studies have shown that psychological factors can influence adherence to treatment in chronic conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants aged 18 years or older
* Diagnosis of severe obstructive sleep apnea (OSA), defined as AHI ≥30
* Signed informed consent for participation in the study
* Adequate physical and psychological capacity to participate in the intervention and complete questionnaires
* Patients who are initiating CPAP therapy at the Sleep Medicine Center, University of Split School of Medicine
* Availability for follow-up over a three-month period

Exclusion Criteria:

* Presence of central sleep apnea or other primary sleep disorders
* Cognitive impairment or psychiatric conditions that may hinder the ability to follow instructions or complete questionnaires
* Previous experience with CPAP therapy prior to study enrollment
* Significant comorbidities (e.g. unstable cardiovascular disease, advanced pulmonary disease) that may interfere with study outcomes
* Pregnancy
* Inability to participate in follow-up assessments or be contacted by telephone

Where this trial is running

Split, Dalmatia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep Apnea
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.