Improving continuity of care for people hospitalized with advanced HIV in Johannesburg.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

A prospective cohort with a nested process evaluation will enroll adults admitted to Helen Joseph Hospital with advanced HIV (CD4 <200 cells/µL and/or WHO stage 3 or 4). Participants provide consent and contact information and are followed after discharge to document linkage to primary healthcare, retention, readmissions, and mortality. The study will map hospital-to-clinic referral pathways and use interviews and service data to identify gaps and barriers in continuity of care. No experimental treatments are given; the goal is to generate evidence to inform strategies that strengthen linkage, retention, and long-term outcomes for people with AHD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Known HIV positive status
* Admitted to inpatient care for an AHD-related illness
* Aged 18 years and above
* Able to provide written consent or consent using a thumbprint
* Consent to be contacted after discharge and can provide contact information

Exclusion Criteria:

* Confined to tuberculosis isolation ward or other wards for patients with acute infectious disease that requires isolation procedures
* Not physically, mentally, or emotionally able to participate in the study prior to discharge, in the opinion of facility or study staff
* Unable to communicate in any of the languages into which the questionnaire has been translated or that is known to the research assistant

Where it's running

• Helen Joseph Hospital
  Johannesburg, Gauteng, South Africa Recruiting

Study contacts

• Principal investigator: Sydney Rosen — Boston University
• Study coordinator: Elizabeth Kachingwe
• Email: ekachingwe@heroza.org
• Phone: ‪27 61 066 3132‬

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.