Improving communication in PTSD treatment

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

NA · Boston University · NCT06088303

This study is testing if adding a writing exercise to standard PTSD treatments can help people feel better by improving communication with their therapists.

Quick facts

PhaseNA
Study typeInterventional
Enrollment54 (estimated)
Ages18 Years and up
SexAll
SponsorBoston University (other)
Locations1 site (Boston, Massachusetts)
Trial IDNCT06088303 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to enhance the effectiveness of existing PTSD treatments, specifically cognitive processing therapy (CPT) and prolonged exposure (PE), by incorporating an Adjunctive Writing intervention for Amplifying Response and Engagement (AWARE). The AWARE intervention involves a brief writing task that encourages patients to articulate their treatment experiences, along with guided therapist responses to foster better communication. The study will compare the outcomes of patients receiving CPT and PE with AWARE against those receiving standard CPT and PE without the writing component. The goal is to determine if improved patient-provider communication can lead to better treatment outcomes for individuals with PTSD.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with PTSD who have been stable on psychiatric medications for at least four weeks.

Not a fit: Patients with current unstable bipolar disorder, psychosis, or severe substance use issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve treatment outcomes for patients with PTSD.

How similar studies have performed: Other studies have shown promise in enhancing therapeutic outcomes through improved patient-provider communication, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of PTSD
* Stable on psychiatric medications for at least 4 weeks

Exclusion Criteria:

* Current unstable bipolar disorder
* Current psychosis
* Current active suicidal or homicidal ideation with intent or plan
* Current severe substance use that warrants immediate medical attention
* Current trauma-focused treatment
* Significant cognitive impairment that would prevent engagement in assessments and therapy (e.g., advanced dementia, severe traumatic brain injury).

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stress Disorders, Post-Traumatic, Posttraumatic stress disorder, Cognitive processing therapy, Prolonged exposure, Adjunctive writing for amplifying response and engagement, Health communication, Patient-provider communication

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.