Improving cognitive abilities in older adults using rehabilitation and electrical stimulation
Official title: Patient-Centered NeuroRehabilitation
Run by University of Michigan · NCT03036319 · Data updated 2026-11-12
This study is testing whether a combination of brain training exercises and electrical stimulation can help older adults with memory and thinking problems improve their cognitive skills.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Status | Recruiting |
| Started | June 2016 |
| Main results expected | November 2027 |
| Study ends | November 2027 |
| Registry record updated | January 14, 2026 |
| Trial ID | NCT03036319 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 50 or older who report cognitive dysfunction or are cognitively intact.
✕Probably not a fit
Patients with a history of epilepsy, significant sensory or motor impairments, or current substance abuse may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of cognitive rehabilitation and transcranial electrical stimulation (TES) in enhancing cognitive abilities among older adults experiencing cognitive deficits. It aims to tailor neurorehabilitation treatments to individual patient needs, focusing on improving tasks related to attention, memory, and problem-solving. The study employs a cross-over design, allowing participants to experience both active and sham TES conditions, and compares different forms of TES, including transcranial direct current stimulation (tDCS) and alternating current stimulation (tACS). The ultimate goal is to maximize cognitive and real-world functioning for older adults with various cognitive impairments.
Why it matters
Potential benefit: If successful, this approach could significantly enhance cognitive functioning and daily living skills for older adults with cognitive deficits.
How similar studies have gone: While the field of TES is relatively new, there is emerging evidence suggesting potential benefits from similar approaches, though this specific combination of interventions is less commonly tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Individuals who have reported cognitive dysfunction and cognitively intact participants. 2. Participants will be age 50 or older Exclusion Criteria: 1. A history of epilepsy 2. Sensory or motor impairments that limit the ability to take part in the study 3. Current alcohol or drug abuse/dependence 4. Those who are currently pregnant or may become pregnant during the duration of the study (if there is a question of pregnancy, pregnancy tests will be available for participants at no charge) Those who are being evaluated for TES methodology will also be excluded for 1) metallic or electronic implant 2) skull plates or other cranial implants that affect TES
Where it's running
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University of Michigan - Department of Psychiatry
Ann Arbor, Michigan, United States Recruiting
Study contacts
- Principal investigator: Benjamin M Hampstead, Ph.D. — University of Michigan
- Study coordinator: Kayla Rinna, M.S.
- Email: krinna@med.umich.edu
- Phone: 734-936-7739
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.