Improving cognitive abilities in older adults using rehabilitation and electrical stimulation
Patient-Centered NeuroRehabilitation
This study is testing whether a combination of brain training exercises and electrical stimulation can help older adults with memory and thinking problems improve their cognitive skills.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Trial ID | NCT03036319 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of cognitive rehabilitation and transcranial electrical stimulation (TES) in enhancing cognitive abilities among older adults experiencing cognitive deficits. It aims to tailor neurorehabilitation treatments to individual patient needs, focusing on improving tasks related to attention, memory, and problem-solving. The study employs a cross-over design, allowing participants to experience both active and sham TES conditions, and compares different forms of TES, including transcranial direct current stimulation (tDCS) and alternating current stimulation (tACS). The ultimate goal is to maximize cognitive and real-world functioning for older adults with various cognitive impairments.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 or older who report cognitive dysfunction or are cognitively intact.
Not a fit: Patients with a history of epilepsy, significant sensory or motor impairments, or current substance abuse may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance cognitive functioning and daily living skills for older adults with cognitive deficits.
How similar studies have performed: While the field of TES is relatively new, there is emerging evidence suggesting potential benefits from similar approaches, though this specific combination of interventions is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Individuals who have reported cognitive dysfunction and cognitively intact participants. 2. Participants will be age 50 or older Exclusion Criteria: 1. A history of epilepsy 2. Sensory or motor impairments that limit the ability to take part in the study 3. Current alcohol or drug abuse/dependence 4. Those who are currently pregnant or may become pregnant during the duration of the study (if there is a question of pregnancy, pregnancy tests will be available for participants at no charge) Those who are being evaluated for TES methodology will also be excluded for 1) metallic or electronic implant 2) skull plates or other cranial implants that affect TES
Where this trial is running
Ann Arbor, Michigan
- University of Michigan - Department of Psychiatry — Ann Arbor, Michigan, United States (Recruiting)
Study contacts
- Principal investigator: Benjamin M Hampstead, Ph.D. — University of Michigan
- Study coordinator: Kayla Rinna, M.S.
- Email: krinna@med.umich.edu
- Phone: 734-936-7739
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.