Improving cervical cancer treatment access in Botswana
Thibang Diphatlha: Testing Adaptive Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
This study is trying out new ways to help women in Botswana get cervical cancer treatment more quickly and easily.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 610 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Abramson Cancer Center at Penn Medicine Academic / other |
| Locations | 3 sites (Philadelphia, Pennsylvania and 2 other locations) |
| Trial ID | NCT05952141 on ClinicalTrials.gov |
What this trial studies
This study tests adaptive strategies to enhance the timely adoption of cervical cancer treatment in Botswana through a pragmatic trial design. It employs a hybrid Sequential Multiple Assignment Randomized Trial (SMART) approach to address patient- and system-level barriers identified in preliminary data, such as delayed communication of results and care coordination issues. The strategies incorporate behavioral economics principles and aim to improve treatment access through centralized outreach and nudge strategies, making them scalable and sustainable for long-term use.
Who should consider this trial
Good fit: Ideal candidates for this study are biological females aged 18 or older with a confirmed diagnosis of invasive cervical cancer in Botswana.
Not a fit: Patients who are biological males or those without a cervix will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the speed and efficiency of cervical cancer treatment access for patients in Botswana.
How similar studies have performed: Other studies have shown success with similar adaptive strategies in improving treatment access in cancer care, indicating potential for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients will be eligible if they: 1. are biological females 2. are aged 18 or older 3. have pathology-confirmed invasive cervical cancer diagnosis 4. have pathology results evaluated at National Health Laboratory in Botswana 5. are citizens of Botswana 6. have no prior history of invasive cervical cancer Exclusion Criteria: Patients will be excluded if they: 1. are biological males or otherwise born without a cervix 2. are below the age of 18 due to the rarity of cervical cancer in this population 3. do not meet study inclusion criteria
Where this trial is running
Philadelphia, Pennsylvania and 2 other locations
- University of Pennsylvania — Philadelphia, Pennsylvania, United States (Active_not_recruiting)
- Nyangabgwe Referral Hospital — Francistown, North-East District, Botswana (Recruiting)
- Princess Marina Hospital — Gaborone, Botswana (Recruiting)
Study contacts
- Principal investigator: Katharine Rendle, PhD,MSW,MPH — University of Pennsylvania
- Study coordinator: Katharine Rendle, PhD,MSW,MPH
- Email: katharine.rendle@pennmedicine.upenn.edu
- Phone: 215-349- 5442
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.