Improving cervical cancer care for women with HIV in South Africa

Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women with HIV in South Africa: Part 2

Not applicable Interventional Boston University Charles River Campus · NCT06182241

This study is trying to find out what stops women with HIV in South Africa from getting timely cervical cancer treatment so they can create better support and care options for them.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years and up
SexFemale
SponsorBoston University Charles River Campus Academic / other
Locations3 sites (Boston, Massachusetts and 2 other locations)
Trial IDNCT06182241 on ClinicalTrials.gov

What this trial studies

This study aims to identify and address barriers that prevent women living with HIV from receiving timely cervical cancer treatment. It involves qualitative interviews with women who have had recent high-risk abnormal Pap smears and healthcare providers to understand their experiences and challenges. Based on these insights, the researchers will develop a multi-level intervention to enhance awareness and retention in cervical cancer care. The intervention will include both patient-level sessions and provider tools to facilitate better care.

Who should consider this trial

Good fit: Ideal candidates for this study are cisgender women aged 18 and older living with HIV who have had a recent high-risk abnormal Pap smear.

Not a fit: Patients who are HIV-negative, younger than 18, or have had recent normal or low-risk Pap results may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve retention in cervical cancer care for women living with HIV, leading to better health outcomes.

How similar studies have performed: Other studies have shown success in addressing similar barriers in healthcare retention, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having a cervix
* Aged 18+
* Living with HIV
* Recent high-risk abnormal Pap results within the last month (if needed, we may increase the range by up to 6 months to ensure that we meet our targets).

Exclusion Criteria:

* Younger than 18 years old
* HIV-negative
* No cervix/history of hysterectomy
* Recent normal or low-risk abnormal Pap results
* Unable to provide informed consent or assent in English or isiZulu and/or have a significant psychiatric illness (e.g., active psychotic disorder or untreated bipolar disorder) that could interfere with participation will be excluded. Potential participants will also be asked if they have any health conditions that make it difficult for them to travel to the clinic.

Where this trial is running

Boston, Massachusetts and 2 other locations

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cervical CancerHiv
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.