Improving care for young children with bronchiolitis

Respiratory Support and Treatment for Efficient and Cost-Effective Care

Not applicable Interventional University of Pittsburgh · NCT05909566

This study is testing if a new support system can help doctors better manage young children with bronchiolitis by using a specific breathing treatment more effectively.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment198 (estimated)
AgesN/A to 2 Years
SexAll
SponsorUniversity of Pittsburgh Academic / other
Locations1 site (Pittsburgh, Pennsylvania)
Trial IDNCT05909566 on ClinicalTrials.gov

What this trial studies

This project aims to enhance the management of acute respiratory illnesses in pediatric patients, specifically focusing on bronchiolitis. It will evaluate whether clinical decision support (CDS) can standardize the initiation and weaning of heated high flow nasal cannula (HHFNC) therapy. The study seeks to improve adherence to established guidelines and ultimately enhance patient-centered outcomes while reducing unnecessary healthcare costs. Conducted at UPMC Children's Hospital of Pittsburgh, this initiative highlights the institution's commitment to advancing pediatric healthcare.

Who should consider this trial

Good fit: Ideal candidates for this study are children under 2 years of age diagnosed with bronchiolitis and exhibiting a work of breathing (WOB) score greater than 2.

Not a fit: Patients who are immunocompromised, immunosuppressed, have chronic lung disease, or congenital heart disease with baseline cardiorespiratory manifestations may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to faster recovery and improved outcomes for children suffering from bronchiolitis.

How similar studies have performed: Other studies have shown promise in using clinical decision support systems to improve adherence to treatment guidelines, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* \<2 years of age Bronchiolitis WOB Score \>2

Exclusion Criteria:

* Immunocompromised
* Immunosuppressed
* Chronic lung disease
* Congenital heart disease with baseline cardiorespiratory manifestations

Where this trial is running

Pittsburgh, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bronchiolitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.