Improving breast cancer risk assessments using health data integration

Integrating EHR and Patient-generated Health Data for Breast Cancer Risk Assessment and Decision Support in a Diverse Multiethnic Population

Not applicable Interventional Columbia University · NCT05810025

This study is testing if combining personal health information with electronic health records can help better assess breast cancer risk for women who are at higher risk.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment55 (estimated)
Ages35 Years to 74 Years
SexFemale
SponsorColumbia University Academic / other
Locations1 site (New York, New York)
Trial IDNCT05810025 on ClinicalTrials.gov

What this trial studies

This study aims to enhance the accuracy of breast cancer risk assessments by integrating patient-generated health data (PGHD) with electronic health records (EHRs). It addresses challenges such as missing data in EHRs and seeks to develop more personalized cancer prevention strategies. The study will evaluate how this integration can improve digital access to health data and support policy goals for interoperability. By focusing on high-risk women, the research intends to streamline risk assessment processes and ultimately improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 35-74 years who are identified as high-risk for breast cancer based on specific risk models.

Not a fit: Patients with a personal history of breast cancer or those who have previously participated in a related sub-study will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate breast cancer risk assessments and better personalized prevention strategies for women at high risk.

How similar studies have performed: Other studies have shown promise in using integrated health data for risk assessments, but this approach is innovative in its specific focus on breast cancer and the use of FHIR technology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women, age 35-74 years
* High-risk defined as 5-year invasive breast cancer risk ≥1.7% or 10 risk ≥20% according to the BCSC or GAIL models
* English- or Spanish-speaking
* Able to sign informed consent.

Exclusion Criteria:

* Women with a personal history of breast cancer
* Women who previously participated in a sub-study (Aim 1) of the awarded grant.

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast CancerElectronic Health RecordDecision AidFast Healthcare Interoperability ResourcesBreast Cancer Risk AssessmentLobular Carcinoma In SituAtypical Hyperplasia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.