Improving balance in stroke survivors using sensory feedback

Multisensory Augmentation to Improve the Standing Balance of People With Chronic Stroke

Early Phase 1 Interventional VA Office of Research and Development · NCT05760885

This study is testing a new way to help stroke survivors improve their balance by using gentle vibrations during a 10-week training program to see if it works better than regular balance exercises.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment36 (estimated)
Ages21 Years and up
SexAll
SponsorVA Office of Research and Development Federal
Locations1 site (Charleston, South Carolina)
Trial IDNCT05760885 on ClinicalTrials.gov

What this trial studies

This study aims to enhance standing balance in individuals who have experienced a stroke by utilizing a novel multisensory augmentation approach. The method involves applying non-invasive vibrations to provide artificial feedback to the nervous system, potentially improving the ability to sense body position and prevent falls. Participants will undergo a 10-week balance training program, with half receiving sensory augmentation to assess its effectiveness compared to standard balance training. Clinical and biomechanical assessments will be conducted before and after the training to evaluate improvements in balance control.

Who should consider this trial

Good fit: Ideal candidates are individuals who have had a stroke at least 6 months prior and have a Berg Balance Scale score of less than 52.

Not a fit: Patients with severe cardiovascular issues, uncontrolled diabetes, or pre-existing neurological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve balance and reduce fall risk for stroke survivors.

How similar studies have performed: While multisensory augmentation is a relatively novel approach, similar studies have shown promise in improving balance in other populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age of at least 21 years;
2. Experience of a stroke at least 6 months prior to participation;
3. Berg Balance Scale score less than 52
4. Ability to stand independently for at least 1 minute without wearing an AFO or other brace that would preclude delivery of stimulation to the ankle or foot sole
5. Provision of informed consent

Exclusion Criteria:

1. Resting blood pressure higher than 220/110 mm Hg
2. History of unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during activities of daily living
3. Pre-existing neurological disorders or dementia
4. Severe visual impairment
5. History of DVT or pulmonary embolism within 6 months
6. Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions

Where this trial is running

Charleston, South Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Stroke
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.