Improving aerobic fitness in older adults with heart conditions
Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults
This study is testing whether a new exercise program that combines high-intensity workouts can help older adults with heart conditions get fitter and feel better compared to a more moderate exercise routine.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 114 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | University of Vermont Medical Center Academic / other |
| Locations | 1 site (South Burlington, Vermont) |
| Trial ID | NCT06951620 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance aerobic fitness and physical function in older adults with cardiovascular disease by comparing two exercise regimens: high intensity interval training (HIIT) combined with high intensity resistance training (HIRT) versus moderate intensity continuous training (MICT) combined with moderate intensity resistance training (MIRT). The research focuses on older cardiac patients who often experience limited benefits from traditional rehabilitation methods. By addressing the unique needs of this population, the study seeks to optimize recovery and improve clinical outcomes. The primary goals are to assess the effectiveness of each training approach in increasing VO2peak and physical function.
Who should consider this trial
Good fit: Ideal candidates are older adults over 65 years old who are ambulatory and enrolled in cardiac rehabilitation following a recent myocardial infarction or percutaneous intervention.
Not a fit: Patients with active malignancies or those unable to comply with the prescribed exercise regimen may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve the recovery and quality of life for older adults recovering from cardiac events.
How similar studies have performed: Previous studies have shown that high intensity interval training can be more effective than moderate intensity training in improving aerobic fitness, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \>65 years old * ambulatory * enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited Exclusion Criteria: * have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance) * unwilling to comply with the exercise prescription they may be assigned to * have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio \<1.0
Where this trial is running
South Burlington, Vermont
- UVMMC Cardiac Rehabilitation — South Burlington, Vermont, United States (Recruiting)
Study contacts
- Principal investigator: Sherrie Khadanga MD, Principal Investigator, MD — University of Vermont Medical Center
- Study coordinator: Patrick Savage, Research Coordinator
- Email: patrick.savage@uvmhealth.org
- Phone: 802-847-4545
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.