Improving adenoma detection during colonoscopy using water exchange and narrow band imaging
PLA Army General Hospital of Beijing
NA · General Hospital of Beijing PLA Military Region · NCT03781648
This study is testing if using water exchange and special imaging during colonoscopy can help doctors find more adenomas in patients.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 360 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | General Hospital of Beijing PLA Military Region (other) |
| Locations | 1 site (Beijing, Dongcheng District) |
| Trial ID | NCT03781648 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of water exchange combined with narrow band imaging (NBI) to enhance adenoma detection rates during colonoscopy. The study involves a prospective, single-blinded, randomized controlled design where patients are assigned to either a control or study group. Experienced endoscopists perform colonoscopies using high-definition equipment, employing water exchange techniques to improve bowel cleanliness and visibility. The goal is to determine if this method can significantly increase the detection of adenomas, particularly in the right colon.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 40 to 85 who are undergoing a colonoscopy and meet the inclusion criteria.
Not a fit: Patients with a history of inflammatory bowel disease, colorectal cancer, or those on anticoagulant therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to higher adenoma detection rates, potentially reducing the risk of colorectal cancer.
How similar studies have performed: Other studies have shown promising results with similar techniques in improving adenoma detection rates, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Any patient ≥40 and \<85 who underwent colonoscopy, does not meet exclusion criteria mentioned below and provide written informed consent will be eligible for enrolment Exclusion Criteria: * • (1) history of inflammatory bowel disease;(2) familial adenomatous polyposis; (3) hereditary non-polyposis colorectal cancer syndrome; (4) personal history of colorectal cancer or had previous colonic resection; (5) haemodialysis; (6) an American Society of Anaesthesiologists class III or higher; (7) antiplatelet or anticoagulant therapy 5 days before the procedure
Where this trial is running
Beijing, Dongcheng District
- Department of Gastroenterology, PLA Army General Hospital — Beijing, Dongcheng District, China (RECRUITING)
Study contacts
- Principal investigator: tianyang zhang — Medical department
- Study coordinator: yuqi he, doctor
- Email: endohe@163.com
- Phone: +801066721299
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Adenoma and Polyp Detection Rates