Improving access to HIV prevention in emergency departments
ED2PrEP - Patient Focused, Low-burden Strategies for PrEP Uptake Among Emergency Departments Patients: a Two-arm Hybrid Implementation-effectiveness Trial
This study is testing new ways to help Black and Latinx communities in the Bronx get access to HIV prevention medication in emergency rooms when they come in for STI care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1416 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Albert Einstein College of Medicine Academic / other |
| Locations | 2 sites (Bronx, New York and 1 other locations) |
| Trial ID | NCT05588193 on ClinicalTrials.gov |
What this trial studies
This study aims to address the inequities in access to HIV pre-exposure prophylaxis (PrEP) among Black and Latinx communities by testing innovative strategies to increase PrEP uptake in emergency departments (EDs) where patients seek care for sexually transmitted infections (STIs). The research focuses on the Bronx, NY, a high-priority area for HIV prevention, and employs an implementation science approach to evaluate two distinct strategies designed to engage patients in PrEP services. By restructuring STI care delivery in EDs, the study seeks to align healthcare services with the needs of at-risk populations, ultimately improving long-term health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older who present to the Montefiore ED with sexual health-related concerns.
Not a fit: Patients who are already HIV-positive or those who are admitted to the hospital from the ED will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly increase PrEP uptake among high-risk populations, thereby reducing HIV incidence in underserved communities.
How similar studies have performed: Other studies have shown promise in utilizing emergency departments for HIV prevention strategies, but this specific approach is innovative and tailored to the unique needs of the Bronx community.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria for Two-Arm Trial: * Patient is \>=18 years at time of index ED visit * Patient presents to one of the Montefiore ED study sites * The ED provider applies at least one of the pre-selected ICD-10 CM codes to the encounter and manual review by SHN confirms the visit is related to sexual health Exclusion Criteria for Two-Arm Trial: * Patient is admitted to the hospital from the ED * Known HIV-positive status
Where this trial is running
Bronx, New York and 1 other locations
- Montefiore Medical Center — Bronx, New York, United States (Recruiting)
- City University of New York — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Uriel Felsen, MD, MS — Albert Einstein College of Medicine
- Study coordinator: Uriel Felsen, MD, MS
- Email: ufelsen@montefiore.org
- Phone: 7189208588
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.