Implant-retained dentures for people with Type 2 diabetes
Clinical and Radiographic Outcomes Around Four Mandibular Implant-retained Overdentures in Individuals With Type 2 Diabetes: A Long-term Retrospective Preliminary Study
This study tests how well implant-supported dentures work for people with Type 2 diabetes who have high blood sugar levels and have been without teeth for a year or more.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 55 Years to 65 Years |
| Sex | All |
| Sponsor | Mansoura University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Mansoura) |
| Trial ID | NCT06206005 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the long-term outcomes of four implant-retained mandibular overdentures in individuals with Type 2 diabetes who have high glycemic levels. It aims to understand how chronic hyperglycemia affects bone resorption and the stability of dental implants. The study will include patients who have been edentulous for at least 12 months and are experiencing issues with denture retention. By analyzing the effects of glycemic control on implant success, the study seeks to provide insights into improving dental care for diabetic patients.
Who should consider this trial
Good fit: Ideal candidates are edentulous individuals with Type 2 diabetes who have experienced issues with mandibular denture retention and have specific bone height measurements.
Not a fit: Patients with well-controlled diabetes or those who do not meet the specific inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of life for diabetic patients by improving denture stability and reducing bone loss.
How similar studies have performed: While there is limited research specifically on this topic, studies have shown that dental implants can be successful in diabetic patients under controlled conditions, suggesting potential for positive outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with edentulous maxilla and mandible for at least 12 months. * Patients have problems with mandibular denture retention and stability. * Patients with a mandibular bone height measured on a panoramic x-ray between 15 and 25 mm at the mandibular symphysis region. Exclusion Criteria: * Patients who did not receive implants at the department clinic. * Patients with more or less than 4 implants in the mandible. * Patients with well controlled diabetics. * Patients with relative contraindications, such as a history of parafunctional habits, daily smokers of more than 10 cigarettes, or alcoholism. * Patients who have previously received head and neck radiation therapy; furthermore, patients receiving intravenous bisphosphonates, chemotherapy, or psychological disorders could jeopardize their cooperation.
Where this trial is running
Mansoura
- Mohammed ELSawy — Mansoura, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohammed Elsawy, PhD
- Email: Dr_sawy@windowslive.com
- Phone: 00201061314522
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.