Impairment-focused versus task-focused walking training for above-knee amputees

Impairment Oriented Versus Task Oriented Gait Training In Transfemoral Amputee Rehabilitation.

Not applicable Interventional Foundation University Islamabad · NCT07578051

This trial will see if impairment-focused strengthening exercises or task-focused real-life walking practice helps adults (18–40) with a single above-knee amputation walk better after a 10-day training program.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorFoundation University Islamabad Academic / other
Locations1 site (Islamabad, Punjab Province)
Trial IDNCT07578051 on ClinicalTrials.gov

What this trial studies

In a randomized controlled trial at Foundation University in Islamabad, 40 unilateral transfemoral amputees aged 18–40 are randomly assigned to two 10-day rehabilitation programs. Both groups receive pre-gait training and corrective walking exercises; Group A receives impairment-oriented strengthening (hip abductors, extensors, flexors, adductors, bridging) with specified holds and repetitions while Group B practices task-oriented functional activities (lateral trunk bending, obstacle stepping, lateral step-ups, walking to visual markers, sit-to-stand with glute focus). Outcome measures include spatiotemporal gait parameters and the Amputee Mobility Predictor (AMP). The design tests which approach produces greater short-term improvements in gait and mobility.

Who should consider this trial

Good fit: Adults 18–40 with a unilateral transfemoral amputation who are medically cleared for physical therapy and willing to attend the program are ideal candidates.

Not a fit: Those with residual limb complications that interfere with mobility, neurological disorders, joint problems in the intact limb, significant cognitive impairment (MoCA <25), uncontrolled diabetes, or current enrollment in another study may not benefit or be eligible.

Why it matters

Potential benefit: If successful, this could help clinicians choose a more effective short-term gait training method to improve walking speed, symmetry, and overall mobility for above-knee amputees.

How similar studies have performed: Task-oriented gait training has shown benefits in other lower-limb amputation and neurological rehabilitation studies, so this trial compares two established approaches in this specific population.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-40 years
* Unilateral transfemoral amputees
* Cleared by physicians for participation in physical therapy
* Willing

Exclusion Criteria:

* Residual limb complication that interfere with mobility
* History of neurological disorders
* Any joint complication in intact limb
* Currently enrolled in another research study
* Mild to severe cognitive impairment (MoCA) i.e , score less than 25 , Uncontrolled diabetes

Where this trial is running

Islamabad, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Transfemoral Amputees
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.