Impact of watching knee injection preparation on treatment effectiveness for osteoarthritis

The Impact of Procedural Awareness of Knee Injections for Osteoarthritis on Patient Perceptions of Effectiveness

Phase 4 Interventional ArthroBiologix Inc. · NCT04111718

This study tests if watching the preparation of knee injections helps adults with osteoarthritis feel better about their treatment results.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment158 (estimated)
Ages50 Years to 80 Years
SexAll
SponsorArthroBiologix Inc. Industry-sponsored
Locations1 site (Hamilton, Ontario)
Trial IDNCT04111718 on ClinicalTrials.gov

What this trial studies

This study investigates whether patients receiving intra-articular platelet-rich plasma (PRP) injections for knee osteoarthritis experience different outcomes based on their awareness of the preparatory steps involved in the procedure. Participants will either observe the preparation of the PRP injections or not, and the study aims to assess how this observation influences their perceptions of treatment effectiveness. The study targets adults aged 50-80 diagnosed with symptomatic knee osteoarthritis and will evaluate the impact of procedural awareness on patient outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 50-80 with symptomatic knee osteoarthritis.

Not a fit: Patients with inflammatory osteoarthritis or those unable to maintain follow-up may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the perceived effectiveness of knee injections for osteoarthritis, leading to improved patient satisfaction and outcomes.

How similar studies have performed: While the specific approach of procedural awareness in this context may be novel, similar studies have shown that patient engagement can positively influence treatment outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult men or women ages 50-80 years
* Diagnosis of symptomatic osteoarthritis of the knee based on clinical and radiographic criteria
* Provision of informed consent

Exclusion Criteria:

* Patients with inflammatory osteoarthritis
* Open wounds or sores over the knee joint
* Patients that will likely have problems, in the judgement of the investigators, with maintaining follow-up

Where this trial is running

Hamilton, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis, Knee
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.