Impact of vestibular lesion location on virtual reality therapy outcomes
Effect of Peripheral Vestibular Pathology Location on the Ability of Home-based Virtual Reality to Improve Symptoms of Peripheral Vestibular Disorders
This study is testing how the location of inner ear damage affects the success of virtual reality therapy for people with balance problems.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of British Columbia Academic / other |
| Locations | 1 site (Vancouver, British Columbia) |
| Trial ID | NCT05424302 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial investigates how the location of lesions in the vestibular system affects the effectiveness of home-based virtual reality therapy for patients with peripheral vestibular disorders. Fifty patients will be recruited and randomly assigned to receive either standard vestibular rehabilitation with virtual reality therapy or a control intervention. Participants will complete symptom questionnaires before and after the intervention period of 4 to 8 weeks. The study aims to personalize vestibular rehabilitation based on lesion location and assess any adverse effects of the virtual reality therapy.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with chronic unilateral or bilateral peripheral vestibular disorders diagnosed through specific vestibular testing.
Not a fit: Patients with central vestibular disorders or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the effectiveness of vestibular rehabilitation by tailoring therapy based on the specific location of vestibular lesions.
How similar studies have performed: While the use of virtual reality in vestibular rehabilitation is emerging, this specific approach focusing on lesion location is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants diagnosed with chronic (≥3 months) unilateral or bilateral peripheral vestibular disorders such as vestibular neuritis, labyrinthitis, Ramsay Hunt syndrome, ischemic lesion and trauma. * Diagnosis made using caloric testing (≥25% reduced vestibular response) and either ocular vestibular evoked myogenic potential (oVEMP) or cervical vestibular evoked myogenic potential (cVEMP) testing. * Participants prescribed vestibular rehabilitation * Participants ≥18 years of age * Access to an android or iOS smart phone Exclusion Criteria: * Pregnant participants * Participant diagnosed with a central vestibular disorder
Where this trial is running
Vancouver, British Columbia
- University of British Columbia — Vancouver, British Columbia, Canada (Recruiting)
Study contacts
- Principal investigator: Desmond A Nunez, MD, MBA — Division of Otolaryngology, Department of Surgery, The University of British Columbia
- Study coordinator: Austin Heffernan, BMSc
- Email: aheff12@student.ubc.ca
- Phone: 604-875-4111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.