Impact of ultrasonic cavitation on healing after tooth extraction
Official title: Effect Of Cavitation In Post-Extractive Socket Healing
Run by International Piezosurgery Academy · NCT06866431 · Data updated 2026-11-12
This study tests if using ultrasonic treatment on tooth extraction sites helps them heal better compared to just using saline irrigation.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | International Piezosurgery Academy Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Trieste, TS) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | March 31, 2026 |
| Study ends | March 31, 2026 |
| Registry record updated | May 28, 2025 |
| Trial ID | NCT06866431 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 100 with two hopeless single-rooted teeth scheduled for extraction.
✕Probably not a fit
Patients with uncontrolled diabetes, autoimmune diseases, or those who have had recent chemotherapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effects of ultrasonic cavitation on the healing process of extraction sockets following the removal of two single-rooted teeth. Participants will undergo a standardized extraction protocol, with one socket receiving ultrasonic treatment using a piezoelectric device while the other serves as a control with saline irrigation. The study aims to monitor the healing outcomes and complications associated with both methods, providing insights into optimal post-extraction care.
Why it matters
Potential benefit: If successful, this approach could enhance healing and reduce complications after tooth extractions.
How similar studies have gone: While the use of piezoelectric devices has shown promise in other contexts, this specific application in post-extraction healing is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 100 years * Two single rooted hopeless teeth of the same arch to be extracted * ASA scale value equal or less than 3 * Signed informed consent Exclusion Criteria: * General contraindications for dental and/or surgical treatments * Inflammatory and autoimmune disease of the oral cavity * Uncontrolled diabetes (HbA1c \> 7.5%) * History of malignancy requiring chemotherapy or radiotherapy within the past five years * Previous immunosuppressant bisphosphonate or high dose corticosteroid therapy * Heavy smokers (\> 20 cigarettes /day) * Pregnancy or lactating women * No compliance * Extraction performed after raising a flap and/or with osteotomy
Where it's running
-
University of Trieste
Trieste, Ts, Italy Recruiting
Study contacts
- Study coordinator: Claudio Stacchi, Dott.
- Email: claudio@stacchi.it
- Phone: +39 0403992254
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.