Impact of ultrasonic cavitation on healing after tooth extraction
Effect Of Cavitation In Post-Extractive Socket Healing
This study tests if using ultrasonic treatment on tooth extraction sites helps them heal better compared to just using saline irrigation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | International Piezosurgery Academy Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Trieste, TS) |
| Trial ID | NCT06866431 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effects of ultrasonic cavitation on the healing process of extraction sockets following the removal of two single-rooted teeth. Participants will undergo a standardized extraction protocol, with one socket receiving ultrasonic treatment using a piezoelectric device while the other serves as a control with saline irrigation. The study aims to monitor the healing outcomes and complications associated with both methods, providing insights into optimal post-extraction care.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 100 with two hopeless single-rooted teeth scheduled for extraction.
Not a fit: Patients with uncontrolled diabetes, autoimmune diseases, or those who have had recent chemotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance healing and reduce complications after tooth extractions.
How similar studies have performed: While the use of piezoelectric devices has shown promise in other contexts, this specific application in post-extraction healing is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 100 years * Two single rooted hopeless teeth of the same arch to be extracted * ASA scale value equal or less than 3 * Signed informed consent Exclusion Criteria: * General contraindications for dental and/or surgical treatments * Inflammatory and autoimmune disease of the oral cavity * Uncontrolled diabetes (HbA1c \> 7.5%) * History of malignancy requiring chemotherapy or radiotherapy within the past five years * Previous immunosuppressant bisphosphonate or high dose corticosteroid therapy * Heavy smokers (\> 20 cigarettes /day) * Pregnancy or lactating women * No compliance * Extraction performed after raising a flap and/or with osteotomy
Where this trial is running
Trieste, TS
- University of Trieste — Trieste, Ts, Italy (Recruiting)
Study contacts
- Study coordinator: Claudio Stacchi, Dott.
- Email: claudio@stacchi.it
- Phone: +39 0403992254
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.