Impact of Tamsulosin on Urinary Retention After Urogynecology Surgery
Official title: Peri-operative Tamsulosin and Impact on Voiding Trial Following Outpatient Urogynecology Surgery: a Randomized Controlled Trial
Run by TriHealth Inc. · NCT06843538 · Data updated 2026-11-12
This study tests if giving tamsulosin before pelvic surgery can help patients avoid needing a catheter after their operation.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 166 (estimated) |
| Sponsor | TriHealth Inc. Academic / other |
| Locations | 1 site (Cincinnati, Ohio) |
| Status | Recruiting |
| Started | February 3, 2025 |
| Main results expected | February 1, 2026 |
| Study ends | June 1, 2026 |
| Registry record updated | February 25, 2025 |
| Trial ID | NCT06843538 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients scheduled for pelvic organ prolapse repair or incontinence surgery.
✕Probably not a fit
Patients with a history of urinary retention requiring catheterization or those undergoing non-urogynecological surgeries may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates whether administering tamsulosin before urogynecology surgeries can reduce the likelihood of patients needing a Foley catheter upon discharge. It focuses on patients undergoing pelvic organ prolapse repair or incontinence surgery. Participants will be randomly assigned to receive either tamsulosin or a placebo to assess the medication's effectiveness in preventing postoperative urinary retention.
Why it matters
Potential benefit: If successful, this approach could lead to fewer patients requiring catheterization after surgery, improving recovery and comfort.
How similar studies have gone: Other studies have explored the use of alpha blockers in similar contexts, showing promising results, but this specific approach is being evaluated in a novel setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- Patients undergoing any pelvic organ prolapse repair or incontinence surgery Exclusion Criteria: * Any surgery involving a non-urogynecologist * Patients already on an alpha blocker * Baseline hypotension * History of syncope * Postural orthostatic tachycardia syndrome (POTS) * Non-English speaker or interpreter unavailable for Spanish-speaking patient * Impaired cognition impeding proper consenting * Any other medical contraindication for tamsulosin use * History of urinary retention requiring continuous or intermittent catheterization * Patients consented for the study but then due to intraoperative complication, routine voiding trial no longer indicated due to requiring indwelling catheter or intermittent catheterization on discharge will be excluded from primary outcome analysis * Pregnancy
Where it's running
-
TriHealth
Cincinnati, Ohio, United States Recruiting
Study contacts
- Study coordinator: Gisele C Moran, MD, MPH
- Email: gisele_moran@trihealth.com
- Phone: 513-862-1123
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.