Impact of socioeconomic factors on outcomes in young breast cancer patients after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to enroll 1000 young breast cancer patients in China, assigning them to three surgical options: breast-conserving surgery, mastectomy alone, and mastectomy with reconstruction. The study will collect data on clinicopathological features, socioeconomic determinants, treatment information, and long-term survival outcomes. Patients will be followed for at least 10 years, with assessments of quality of life, psychological well-being, and decision-making factors at regular intervals. The primary focus is to understand how socioeconomic factors influence patient-reported outcomes post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 50 years old.
* The surgery time and procedure have been confirmed, and the surgical informed consent and research informed consent forms have been signed.
* Informed consent obtained from patient.
* Unilateral Breast Cancer.
* Good health,the patient is able to tolerate general anesthesia and surgery, with an ECOG performance status of ≤2 points.
* No history of breast/axillary radiation therapy.
* Willing and capable of complying with the study protocol visits, treatment plans, and other research procedures.

Exclusion Criteria:

* Bilateral breast cancer.
* Inflammatory breast cancer.
* Stage IV breast cancer.
* Physical examination and imaging suggest tumor infiltration into the skin, pectoralis major muscle, and other adjacent tissues.
* Patients unable to tolerate surgery due to coagulation abnormalities.
* In patients without evidence of breast cancer in the contralateral breast, requesting contralateral prophylactic mastectomy.
* In patients who have undergone surgical treatment for breast cancer (including mastectomy, breast-conserving surgery, and mastectomy with implant reconstruction), requesting secondary breast surgery.
* Patients with a history or current diagnosis of other malignancies, excluding thyroid cancer.
* The conditions considered unsuitable for inclusion by researchers.

Where it's running

• Sun Yat-sen Memorial Hospital,Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Kai Chen, MD
• Email: chenkai23@mail.sysu.edu.cn
• Phone: 15920164730

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.