Impact of socioeconomic factors on chemical exposure and DNA damage in children
Socioeconomic Determinants of the Chemical Exposome and Its Genotoxic Effects in Children
This study looks at how a child's family income and background can affect their exposure to harmful chemicals and any resulting DNA damage.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 140 (estimated) |
| Ages | 8 Years to 12 Years |
| Sex | All |
| Sponsor | Institut Cancerologie de l'Ouest Academic / other |
| Locations | 1 site (Saint-Herblain) |
| Trial ID | NCT06314633 on ClinicalTrials.gov |
What this trial studies
This study examines how socioeconomic position affects children's exposure to environmental chemicals and the resulting DNA damage. It includes children aged 8 to 12 from various socioeconomic backgrounds living in the Pays de la Loire region. The methodology involves collecting hair samples to detect chemical pollutants and assessing DNA damage, alongside administering socioeconomic questionnaires. The goal is to understand the relationship between social inequalities, chemical exposure, and health risks in children.
Who should consider this trial
Good fit: Ideal candidates are children aged 8 to 12 years old living in the Pays de la Loire region.
Not a fit: Patients with disorders that prevent them from understanding trial information or providing informed assent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how socioeconomic factors influence children's health risks related to chemical exposures.
How similar studies have performed: While studies have explored the impact of environmental exposures on health, this specific focus on socioeconomic determinants in children is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children over 8 and under 12 years old at the time of inclusion * Children in school in class level CE2, CM1 or CM2 * Living in the Pays de La Loire region, at least 80% of the time * Written informed assent and consent obtained from the participant and both parents or legal representative prior to performing any protocol-related procedures. Exclusion Criteria: \- Disorder precluding understanding of trial information or informed assent.
Where this trial is running
Saint-Herblain
- Institut de Cancérologie de l'ouest — Saint-Herblain, France (Recruiting)
Study contacts
- Study coordinator: Marie ROBERT, MD
- Email: Marie.Robert@ico.unicancer.fr
- Phone: +33240679900
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.