Impact of simulated microgravity on female pelvic blood flow
Female Pelvic Blood Flow Under Simulated Microgravity
This study tests how lying in a head-down position, which simulates being in space, affects blood flow to the reproductive organs in healthy women aged 18 to 44.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 18 Years to 44 Years |
| Sex | Female |
| Sponsor | Koc University Hospital Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06633692 on ClinicalTrials.gov |
What this trial studies
This study investigates how simulated microgravity affects blood flow to female reproductive organs using Doppler velocimetry. By placing participants in a head-down tilt position, researchers aim to replicate the physiological changes experienced during spaceflight. The study focuses on understanding the redistribution of blood circulation and vascular dynamics in healthy women aged 18-44. This research is crucial as space missions become more frequent, highlighting the need for insights into women's health in microgravity environments.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy females aged 18-44 without a history of reproductive tract pathologies or cardiovascular diseases.
Not a fit: Patients who have undergone hysterectomy or oophorectomy, are pregnant, or have premature ovarian insufficiency will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of female reproductive health in space, potentially leading to improved health outcomes for women during long-duration space missions.
How similar studies have performed: While there is limited information on pelvic blood flow under microgravity, similar studies on cardiovascular responses to microgravity have shown significant physiological changes, indicating potential for success in this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-44 years old healthy female individuals Exclusion Criteria: * History of hysterectomy and/or oophorectomy * Pregnancy * Premature ovarian insufficiency * Women with reproductive tract pathologies * Cardiovascular diseases
Where this trial is running
Istanbul
- Koc Universoty Hospital — Istanbul, Turkey (Recruiting)
Study contacts
- Principal investigator: Afak Durur Karakaya, M.D. — Koç University
- Study coordinator: Ceren Unal, M.D.
- Email: cunal@kuh.ku.edu.tr
- Phone: +902124678700
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.