Impact of seaweed food additive carrageenan on gut health

Investigating the Impact of the Seaweed Derived Food Additive, Carrageenan, on the Human Gut Microbiome

Not applicable Interventional University of Reading · NCT06738329

This study tests whether a seaweed food additive called carrageenan can improve gut health in healthy people by changing their gut bacteria and making them feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment99 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorUniversity of Reading Academic / other
Locations1 site (Reading, Reading)
Trial IDNCT06738329 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of carrageenan, a seaweed-derived food additive, on the human gut microbiome. Healthy participants will consume either a gummy sweet containing carrageenan and inulin or a placebo for four weeks, with stool and urine samples collected at three intervals. The study aims to determine if these products can positively alter gut bacterial composition and improve gastrointestinal comfort. The design is randomized and double-blind to ensure unbiased results.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals without any gut disorders or recent antibiotic use.

Not a fit: Patients with gut disorders such as IBS or IBD, or those with food allergies or intolerances, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to healthier snack options that promote gut health.

How similar studies have performed: While there have been lab-based experiments showing potential benefits, this approach in humans is relatively novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy individuals

Exclusion Criteria:

* Prescribed antibiotics in the last 3 months
* Individuals with any gut disorders such as IBS or IBD
* individuals with any food allergies or intolerances
* Individuals who regularly consume pre or probiotics

Where this trial is running

Reading, Reading

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Gut MicrobiomeHealthy DonorsCarrageenanGut microbiomeGut healthfood additive
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.