Impact of non-nutritive sucking on feeding tolerance in premature infants
Effect of Non-nutritive Sucking on Feeding Intolerance in Premature Infants
NA · Chang Gung Memorial Hospital · NCT06065839
This study tests if letting premature infants suck on something non-nutritive for a short time can help them tolerate feeding better before they need tube-feeding.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 180 (estimated) |
| Ages | 26 Weeks to 32 Weeks |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital (other) |
| Locations | 1 site (Taoyuan, Kwei-Shan District) |
| Trial ID | NCT06065839 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of non-nutritive sucking on feeding intolerance in premature infants. Participants are randomly assigned to one of three groups: one receiving 5 minutes of non-nutritive sucking, another receiving 15 minutes, and a control group with no non-nutritive sucking. The study controls for various factors such as gestational age, birth weight, and type of milk fed. The aim is to determine if non-nutritive sucking can improve feeding tolerance before tube-feeding in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates are premature infants between 26 to 31 weeks gestational age who are being tube-fed.
Not a fit: Patients with severe medical conditions such as congenital anomalies or significant gastrointestinal issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance feeding tolerance in premature infants, potentially leading to better health outcomes.
How similar studies have performed: While the specific approach of this study may be novel, similar interventions have shown promise in improving feeding outcomes in premature infants.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Premature infants whose gestational age is more than 26 weeks (inclusive) to less than 32 weeks * Premature neonates who are force-fed with orogastric or nasogastric tubes * No congenital gastrointestinal abnormalities * No serious Congenital anomalies and heart disease, no cleft lip and palate * Never received stomach or intestinal surgery * No central nervous system damage * With the consent of their parents or guardians, and fill out the consent form. Exclusion Criteria: * Severe hypoxemia * Severe hypotension * Esophageal perforation * Necrotic enteritis * Infection-induced sepsis * 3-4 grades of ventricular hemorrhage
Where this trial is running
Taoyuan, Kwei-Shan District
- Chang Gung Memorial Hospital — Taoyuan, Kwei-Shan District, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Yu-Ting HUANG, BSN — Chang Gung Memorial Hospital
- Study coordinator: Yu-Ting HUANG, BSN
- Email: Bunny@cgmh.org.tw
- Phone: +886975832680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Non-nutritive Sucking