Clinical trial Recruiting at 1 site Observational Ages 21 and up

Impact of Night Shift Work on Obesity Risk in Workers

Official title: Development and Evaluation of Nutritional Strategies to Reduce and Prevent Obesity in Shiftworkers

Run by University of Vienna · NCT06288568 · Data updated 2026-11-12

This study is trying to see if working night shifts makes hospital and industry workers more likely to become obese compared to those who work during the day.

Quick facts

Study typeObservational
Ages21 Years and up
SexAll
Enrollment1000 (estimated)
SponsorUniversity of Vienna
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Vienna, State of Vienna)
StatusRecruiting
StartedApril 1, 2024
Main results expectedNovember 1, 2025
Study endsMay 31, 2028
Registry record updatedSeptember 8, 2025
Trial IDNCT06288568 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include healthcare and industrial workers aged 21 and older who have been working rotating night shifts for at least three years.

Probably not a fit

Patients who have a BMI of 40 or above, are pregnant, or have chronic diseases requiring ongoing therapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how night shift work affects obesity risk among hospital and industry workers across five European countries. By recruiting 1000 participants, including both rotating night shift workers and day workers, the study aims to explore the biological, behavioral, and environmental mechanisms linking night shift work to obesity. Participants will be matched by age, gender, and work tasks to ensure a comprehensive analysis of the effects of shift work on metabolic health.

Why it matters

Potential benefit: If successful, this study could provide insights into the mechanisms of obesity risk associated with night shift work, potentially leading to targeted interventions for affected workers.

How similar studies have gone: While the relationship between shift work and obesity has been noted, this specific mechanistic approach in real-life shift workers is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria shift worker

* Health care sector or industrial shift worker
* Employed or self-employed
* 21 years or older
* ≥ 24 h/ week
* Shift work duration \> 3 years and currently doing night shifts
* 4 or more rotating night shifts/month (night shift defined as a work schedule that involves working at least 3 hours between 00:00 and 5:00), at least 2 consecutive nights/month

Inclusion criteria controls

* Health care sector or industrial work
* Employed or self-employed
* 21 years or older
* ≥ 24 h/ week
* No night shift or rotating shift work in the last 5 years
* No history of night shift or rotating shift work for more than 5 years

Exclusion Criteria shift worker and controls:

* Pregnancy
* Lactation period
* BMI of 40 kg/m2 or above
* Present treatment of a disease e.g. cancer radio- or chemotherapy
* Chronic diseases if in an ongoing therapy but not after a remission (renal failure, active hepatitis, cirrhosis, myocardial infarction, chronic obstructive pulmonary disease and cancer)
* Immunodeficiency syndrome, any auto-immune or auto-inflammatory diseases (e.g. type-1 diabetes, multiple sclerosis, lupus, rheumatoid arthritis) and acute episodes of atopic diseases (atopic dermatitis, asthma, type 1 allergies such as hay fever)
* Bariatric surgery
* Antibiotics in the last month

Where it's running

  • Medical University of Vienna
    Vienna, State of Vienna, Austria
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.