Impact of new epilepsy diagnostic criteria on outcomes after a first seizure
Official title: Monocentric Study to Investigate the Effect of the New Definition of Epilepsies of the International League Against Epilepsy of 2014 on the Diagnosis After the First Seizure, on Patient Satisfaction, Cognition and Health Economic Factors
Run by University Hospital Marburg · NCT06836687 · Data updated 2026-11-12
This study looks at how new guidelines for diagnosing epilepsy affect people who have just had their first seizure, focusing on their seizure frequency, medication use, quality of life, and thinking skills.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital Marburg Academic / other |
| Locations | 1 site (Marburg, Hesse) |
| Status | Recruiting |
| Started | March 1, 2018 |
| Main results expected | April 1, 2038 |
| Study ends | August 1, 2038 |
| Registry record updated | February 20, 2025 |
| Trial ID | NCT06836687 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 18 and older who have experienced their first epileptic seizure.
✕Probably not a fit
Patients with a history of chronic drug or alcohol abuse in the last two years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effects of the 2014 International League Against Epilepsy's new diagnostic criteria on patients experiencing their first epileptic seizure. It aims to assess seizure frequency, medication adherence, quality of life, and cognitive performance following the initial seizure. By utilizing advanced imaging techniques, the study seeks to better classify patients with structural epilepsy and improve early treatment outcomes. The research will also evaluate neuropsychological deficits and the socio-economic impact of a first seizure.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients experiencing their first seizure, enhancing their quality of life.
How similar studies have gone: Other studies have shown that improved diagnostic criteria can lead to better treatment outcomes, suggesting this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Completion of the 18th year of life * first epileptic seizure * Ability to understand the patient information and to give written consent * Written consent for voluntary participation in the study Exclusion Criteria: * Chronic drug or alcohol abuse in the last two years
Where it's running
-
c/o Klinik für Neurologie
Marburg, Hesse, Germany Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.