Impact of new epilepsy diagnostic criteria on outcomes after a first seizure
Monocentric Study to Investigate the Effect of the New Definition of Epilepsies of the International League Against Epilepsy of 2014 on the Diagnosis After the First Seizure, on Patient Satisfaction, Cognition and Health Economic Factors
This study looks at how new guidelines for diagnosing epilepsy affect people who have just had their first seizure, focusing on their seizure frequency, medication use, quality of life, and thinking skills.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Marburg Academic / other |
| Locations | 1 site (Marburg, Hesse) |
| Trial ID | NCT06836687 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effects of the 2014 International League Against Epilepsy's new diagnostic criteria on patients experiencing their first epileptic seizure. It aims to assess seizure frequency, medication adherence, quality of life, and cognitive performance following the initial seizure. By utilizing advanced imaging techniques, the study seeks to better classify patients with structural epilepsy and improve early treatment outcomes. The research will also evaluate neuropsychological deficits and the socio-economic impact of a first seizure.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older who have experienced their first epileptic seizure.
Not a fit: Patients with a history of chronic drug or alcohol abuse in the last two years may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for patients experiencing their first seizure, enhancing their quality of life.
How similar studies have performed: Other studies have shown that improved diagnostic criteria can lead to better treatment outcomes, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Completion of the 18th year of life * first epileptic seizure * Ability to understand the patient information and to give written consent * Written consent for voluntary participation in the study Exclusion Criteria: * Chronic drug or alcohol abuse in the last two years
Where this trial is running
Marburg, Hesse
- c/o Klinik für Neurologie — Marburg, Hesse, Germany (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.