Clinical trial Recruiting at 1 site Observational Ages 18 and up

Impact of Mitral Valve Prolapse Location on Mitral Plasty Outcomes

Official title: Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty

Run by Centre Hospitalier Universitaire, Amiens · NCT03113552 · Data updated 2026-11-12

This study looks at how the location of mitral valve problems affects the success of surgery for patients who had mitral plasty between 1988 and 2011.

More Mitral Valve Prolapse trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1500 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens, Picardie)
StatusRecruiting
StartedFebruary 4, 2013
Main results expectedJuly 4, 2028
Study endsJuly 4, 2028
Registry record updatedMay 23, 2023
Trial IDNCT03113552 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who underwent mitral plasty between 1988 and 2011 with a diagnosed valvular prolapse.

Probably not a fit

Patients with ischemic mitral insufficiency, significant aortic valvulopathy, or a history of cardiac surgery may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how the location of mitral valve prolapse affects the long-term results of mitral plasty in patients. It focuses on patients who underwent surgery between 1988 and 2011 and had a diagnosed valvular prolapse. The study aims to evaluate the relationship between the geometry of the mitral valve and the success of the surgical intervention, considering factors such as whether the prolapse is monovalvular or bivalvular. By analyzing clinical evaluations and echocardiographic data, the study seeks to provide insights into optimizing surgical outcomes for mitral insufficiency.

Why it matters

Potential benefit: If successful, this study could enhance surgical strategies for mitral valve repair, leading to improved long-term outcomes for patients with mitral valve prolapse.

How similar studies have gone: While the specific approach of this study may be novel, similar studies have indicated that the location of mitral valve prolapse can significantly influence surgical outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients operated between 1988 and 2011
* Presence of a valvular prolapse diagnosed by echocardiography
* Possibility of a complete clinical evaluation at the time of the initial echocardiography

Exclusion Criteria:

* Ischemic MI (including papillary muscle rupture)
* Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease
* History of cardiac surgery

Where it's running

  • CHU Amiens Picardie
    Amiens, Picardie, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.