Impact of Mitral Valve Prolapse Location on Mitral Plasty Outcomes
Official title: Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty
Run by Centre Hospitalier Universitaire, Amiens · NCT03113552 · Data updated 2026-11-12
This study looks at how the location of mitral valve problems affects the success of surgery for patients who had mitral plasty between 1988 and 2011.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Status | Recruiting |
| Started | February 4, 2013 |
| Main results expected | July 4, 2028 |
| Study ends | July 4, 2028 |
| Registry record updated | May 23, 2023 |
| Trial ID | NCT03113552 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who underwent mitral plasty between 1988 and 2011 with a diagnosed valvular prolapse.
✕Probably not a fit
Patients with ischemic mitral insufficiency, significant aortic valvulopathy, or a history of cardiac surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates how the location of mitral valve prolapse affects the long-term results of mitral plasty in patients. It focuses on patients who underwent surgery between 1988 and 2011 and had a diagnosed valvular prolapse. The study aims to evaluate the relationship between the geometry of the mitral valve and the success of the surgical intervention, considering factors such as whether the prolapse is monovalvular or bivalvular. By analyzing clinical evaluations and echocardiographic data, the study seeks to provide insights into optimizing surgical outcomes for mitral insufficiency.
Why it matters
Potential benefit: If successful, this study could enhance surgical strategies for mitral valve repair, leading to improved long-term outcomes for patients with mitral valve prolapse.
How similar studies have gone: While the specific approach of this study may be novel, similar studies have indicated that the location of mitral valve prolapse can significantly influence surgical outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients operated between 1988 and 2011 * Presence of a valvular prolapse diagnosed by echocardiography * Possibility of a complete clinical evaluation at the time of the initial echocardiography Exclusion Criteria: * Ischemic MI (including papillary muscle rupture) * Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease * History of cardiac surgery
Where it's running
-
CHU Amiens Picardie
Amiens, Picardie, France Recruiting
Study contacts
- Study coordinator: Catherine SZYMANSKI, Dr
- Email: szymanski.catherine@chu-amiens.fr
- Phone: +33322455885
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Predicting high-risk arrhythmic events in people with arrhythmic mitral valve prolapse
This study tests a risk model to see which patients with arrhythmic mitral valve prolapse might need an ICD.
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AI and 3D ultrasound mapping of mitral valve prolapse shape and function.
This project tests an automated AI system that uses intraoperative 3D transesophageal ultrasound to map mitral valve anatomy and create patient-specific biomechanical models for adults having surgery for degenerative mitral valve prolapse.
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Korea VHD Echo Study: Real-World Practice of Aortic, Mitral, and Tricuspid Valves
This study looks at how valvular heart disease is managed in Korea by reviewing echocardiograms and medical records from multiple centers to see patterns in disease progression and treatment.
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Patient-centered decision-making for mitral valve prolapse treatment
This study is trying to understand what patients with mitral valve prolapse and their doctors think about choosing between two treatment options, surgery or a less invasive procedure, to help improve how they make decisions together.
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Predicting heart muscle scarring in patients with mitral valve prolapse
This study is trying to find out if a new scoring system can help identify patients with mitral valve prolapse who are at risk for heart muscle scarring and related problems using heart imaging.
-
Impact of mitral valve surgery on ventricular arrhythmias
This study is testing how mitral valve surgery helps people with mitral valve prolapse and arrhythmias by looking at their heart health before and after the operation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.