Impact of Mitral Valve Prolapse Location on Mitral Plasty Outcomes
Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty
This study looks at how the location of mitral valve problems affects the success of surgery for patients who had mitral plasty between 1988 and 2011.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Trial ID | NCT03113552 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how the location of mitral valve prolapse affects the long-term results of mitral plasty in patients. It focuses on patients who underwent surgery between 1988 and 2011 and had a diagnosed valvular prolapse. The study aims to evaluate the relationship between the geometry of the mitral valve and the success of the surgical intervention, considering factors such as whether the prolapse is monovalvular or bivalvular. By analyzing clinical evaluations and echocardiographic data, the study seeks to provide insights into optimizing surgical outcomes for mitral insufficiency.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who underwent mitral plasty between 1988 and 2011 with a diagnosed valvular prolapse.
Not a fit: Patients with ischemic mitral insufficiency, significant aortic valvulopathy, or a history of cardiac surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance surgical strategies for mitral valve repair, leading to improved long-term outcomes for patients with mitral valve prolapse.
How similar studies have performed: While the specific approach of this study may be novel, similar studies have indicated that the location of mitral valve prolapse can significantly influence surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients operated between 1988 and 2011 * Presence of a valvular prolapse diagnosed by echocardiography * Possibility of a complete clinical evaluation at the time of the initial echocardiography Exclusion Criteria: * Ischemic MI (including papillary muscle rupture) * Presence of significant aortic valvulopathy, mitral valvular stenosis or congenital disease * History of cardiac surgery
Where this trial is running
Amiens, Picardie
- CHU Amiens Picardie — Amiens, Picardie, France (Recruiting)
Study contacts
- Study coordinator: Catherine SZYMANSKI, Dr
- Email: szymanski.catherine@chu-amiens.fr
- Phone: +33322455885
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.