Impact of Maximal Strength Training on COPD Patients
Official title: Study on Impact of Maximal Strength Training in Patients With COPD: Physiological and Clinical Implications
Run by Istituti Clinici Scientifici Maugeri SpA · NCT03799354 · Data updated 2026-11-12
This study is testing whether combining strength training with endurance training can help people with COPD improve their exercise ability and muscle function.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 1 site (Lumezzane, Brescia) |
| Status | Recruiting |
| Started | September 18, 2019 |
| Main results expected | February 28, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT03799354 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with COPD who have a stable clinical condition and meet specific pulmonary function criteria.
✕Probably not a fit
Patients with other pulmonary diseases, metabolic disorders, or recent respiratory infections may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of Maximal Strength Training (MST) combined with Endurance Training (ET) on patients with Chronic Obstructive Pulmonary Disease (COPD). It aims to assess improvements in exercise tolerance and muscle function, particularly focusing on the Rate of Force Development (RFD) and aerobic endurance. The study includes patients who meet specific COPD criteria and excludes those with other significant health issues. The methodology involves structured training sessions designed to enhance physical capabilities without adverse effects.
Why it matters
Potential benefit: If successful, this approach could significantly improve the quality of life and physical function in COPD patients.
How similar studies have gone: Previous studies have shown positive outcomes with resistance training in COPD patients, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * COPD clinical definition according to GOLD guidelines with forced expiratory volume (FEV1)/ forced vital capacity (FVC) \< 70%, and FEV1 \< 50% of predicted * stable clinical condition Exclusion Criteria: * pulmonary diseases other than COPD * type II diabetes or other metabolic diseases * malign disease * a respiratory tract infection within the last 4 wks * long oxygen therapy use.
Where it's running
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ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane
Lumezzane, Brescia, Italy Recruiting
Study contacts
- Principal investigator: Mara Paneroni, MSc, PT — Istituti Clinici Scientifici Maugeri
- Study coordinator: Mara Paneroni, MSc, PT
- Email: mara.paneroni@icsmaugeri.it
- Phone: 0039+030+8253
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.