Impact of malnutrition on liver and spleen stiffness in children
Official title: Impact of Malnutrition on Liver and Spleen Stiffness in Children Evaluated by Shear Wave Elastography
Run by Selcuk University · NCT06932445 · Data updated 2026-11-12
This study looks at how malnutrition affects the stiffness of the liver and spleen in children compared to healthy kids.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Month to 18 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Selcuk University Academic / other |
| Locations | 1 site (Konya, Konya) |
| Status | Recruiting |
| Started | April 10, 2025 |
| Main results expected | May 15, 2025 |
| Study ends | May 20, 2025 |
| Registry record updated | April 17, 2025 |
| Trial ID | NCT06932445 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 6 to 18 years diagnosed with malnutrition according to WHO criteria.
✕Probably not a fit
Patients with chronic diseases or those who have undergone liver or spleen surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates how malnutrition affects liver and spleen stiffness in children using shear wave elastography. It includes two groups: children diagnosed with malnutrition and age-matched healthy controls. Participants will undergo non-invasive measurements of organ stiffness performed by a pediatric radiologist who is unaware of their nutritional status. The study aims to provide insights into the early organ-level changes associated with pediatric malnutrition.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and early detection of organ damage in malnourished children.
How similar studies have gone: While there is limited data on this specific approach, similar studies using elastography have shown promise in assessing organ stiffness in various conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children aged 6 to 18 years. * Diagnosis of malnutrition based on World Health Organization (WHO) criteria (for malnutrition group). * Healthy children without any chronic illness (for control group). Exclusion Criteria: * Children with chronic diseases (e.g., liver disease, diabetes, immunocompromised conditions). * Children who have previously undergone liver or spleen surgery. * Children with inability to cooperate during elastography measurement.
Where it's running
-
Selçuk University Faculty of Medicine
Konya, Konya, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mehmet Akif AGIR, Medical Doctor
- Email: mehmetakif_68@hotmail.com
- Phone: +905052910809
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.