Impact of flapless piezoincision on periodontal health during orthodontic treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effects of flapless piezoincision-assisted orthodontics with two different types of grafting: soft tissue grafting and bone grafting. The study will involve non-growing patients requiring orthodontic treatment for dental malocclusion and maxillary deficiency. Participants will undergo a series of assessments, including imaging and periodontal examinations, to evaluate changes in hard and soft tissues. The trial is designed as a single-blind, parallel group randomized controlled trial to ensure objective measurement of outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients will be consecutively selected among those attending the Faculty of Odontology, University Complutense (Madrid, Spain) looking for orthodontic therapy.

The inclusion criteria will be as follows:

* patients requiring maxillary and/or mandible orthodontic treatment;
* patients with permanent dentition in stage 5 or 6 of the cervical vertebral maturation method as described by Baccetti et al. (2002);
* minimal to moderate maxillary and/or mandibular anterior crowding at baseline (arch length discrepancy from 3-8 mm); and
* adequate oral health (i.e. periodontal health, absence of periapical infections and untreated caries).

Exclusion Criteria:

* subjects with periodontitis stage III or IV (Papapanou et al., 2018);
* subjects with poor oral hygiene (represented as full-mouth plaque scores (FMPS) \>25%);
* ongoing chronic drug therapy influencing bone metabolism (e.g. steroids, immunosuppressors or antiresorptive drugs);
* subjects with uncontrolled systemic diseases (e.g. diabetes);
* pregnancy and
* subjects not willing to comply with the study visits

Where it's running

• Faculty of Odontology, University Complutense Madrid
  Madrid, Spain Recruiting

Study contacts

• Study coordinator: Eduardo Montero, Prof
• Email: eduardomonterosolis@ucm.es
• Phone: +34 91 3941901

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Single-surgery Bone Ring Technique for Sinus Lift and Dental Implant in the Back of the Upper Jaw

  This study tests a one-step Bone Ring Technique to lift the sinus and place a dental implant in patients with very thin upper jaw bone.

  Recruiting Damascus University · Damascus, Governorate · NCT07619846

• Myo Munchee versus Oral Motor Therapy to improve upper-jaw growth and mouth muscle function in young children

  This will see if the Myo Munchee mouth device works better than standard oral motor therapy to improve upper-jaw development and mouth muscle function in children ages 3 to 5.

  Recruiting at 2 sites Myo Munchee (Operations) Pty Ltd · Chicago, Illinois and 1 other locations · NCT07088055

• Using clear aligners to expand the upper dental arch in children with cleft lip and palate

  This study is testing if clear aligners can help expand the upper jaw in children aged 6-8 with cleft lip and palate.

  Recruiting Cairo University · Cairo, Select · NCT06994754

• Comparing two ways to widen the upper jaw: MARPE versus SARME

  The team will test whether mini‑screw–assisted expansion (MARPE) or surgically‑assisted expansion (SARME) better widens the upper jaw and how each method changes nasal and sinus structures in people aged 15 and older with maxillary transverse deficiency.

  Recruiting Bezmialem Vakif University · Istanbul, Fatih · NCT07326345

• 3D comparison of maxillary expansion methods in children

  This project tests whether the Invisalign Palatal Expander or traditional rapid maxillary expansion better widens the upper jaw in children with maxillary transverse deficiency.

  Recruiting Bezmialem Vakif University · Istanbul, Fatih · NCT07262892

• 3D-printed versus conventional Hyrax expanders to widen the upper jaw in adolescents

  This compares a 3D-printed Hyrax expander with a conventional Hyrax to see which widens the upper jaw better in adolescents with maxillary transverse deficiency.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07411092

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.