Impact of exercise on quality of life in children with leukemia receiving chemotherapy
Physical Activity and Quality of Life in Pediatric Patients With Acute Lymphoblastic Leukemia Receiving Maintenance Chemotherapy
This study tests if regular exercise can improve the mood and overall quality of life for children aged 8-18 with leukemia who are receiving chemotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 8 Years to 18 Years |
| Sex | All |
| Sponsor | Connecticut Children's Medical Center Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Hartford, Connecticut) |
| Trial ID | NCT03132948 on ClinicalTrials.gov |
What this trial studies
This study evaluates how physical activity influences the quality of life in pediatric patients aged 8-18 with acute lymphoblastic leukemia (ALL) who are undergoing maintenance chemotherapy. It aims to assess the relationship between exercise, mood, energy levels, and psychological well-being, as well as to explore potential biomarkers related to sleep quality. The study addresses a significant gap in research regarding the effects of exercise on children with cancer, an area that has been more extensively studied in adults. Participants will engage in moderate physical activity, and their responses will be measured through surveys and blood samples.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients aged 8-18 with acute lymphoblastic leukemia currently in the maintenance phase of chemotherapy.
Not a fit: Patients who are not undergoing chemotherapy or are outside the age range of 8-18 years will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of life for children with leukemia by promoting physical activity as a beneficial intervention during treatment.
How similar studies have performed: While there is substantial research on exercise benefits in adult cancer patients, this specific approach in pediatric oncology is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric oncology patients with ALL in the maintenance phase of chemotherapy during the time of study * Ages 8-18 years of either gender (age limits due to reliability and validity of outcome assessment surveys) * Have no documented or observable psychiatric or neurological disorders that would interfere with study participation * Capable of speaking and reading English * Having no contraindications to participate in moderate physical exercise as determined by the research staff and the patient's pediatric oncologist * Currently living with their parents/legal guardians * Consent obtained from legal guardians and assent obtained from patients to participate in the study Exclusion Criteria: * Not a pediatric oncology patient with ALL in maintenance * Not receiving chemotherapy during the time of study * Age less than 8 years or greater than 18 years * Not English-speaking Since not all outcome measures have been validated in Spanish and other languages, only English-speaking patients will be included.
Where this trial is running
Hartford, Connecticut
- Connecticut Children's Medical Center — Hartford, Connecticut, United States (Recruiting)
Study contacts
- Principal investigator: Andrea Orsey, MD — Connecticut Children's Medical Center
- Study coordinator: Andrea Orsey, MD
- Email: aorsey@ccmckids.org
- Phone: 860-545-9630
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.