Impact of exercise on obstructive sleep apnea severity

Effects of Physical Activity on OSA Severity Based on the Level of Fluid Shift in Patients Who Can't Use CPAP or MAD

Not applicable Interventional University Hospital, Grenoble · NCT04623463

This study is testing if regular exercise can help reduce the severity of obstructive sleep apnea in adults who aren't currently being treated.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment62 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorUniversity Hospital, Grenoble Academic / other
Locations1 site (Grenoble)
Trial IDNCT04623463 on ClinicalTrials.gov

What this trial studies

This study investigates how physical activity affects the severity of obstructive sleep apnea (OSA) in patients who are not currently receiving treatment. It aims to identify which characteristics of patients influence their response to exercise as a potential intervention for OSA. The study will include individuals aged 18 to 80 with a specific severity of OSA and will assess the effects of regular physical activity on their condition. By understanding these dynamics, the research seeks to provide alternative management strategies for those unable to use traditional therapies.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 80 with moderate to severe obstructive sleep apnea who are not currently undergoing any treatment.

Not a fit: Patients with a BMI over 30 kg/m² or those with certain medical conditions that could affect the results may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a non-invasive treatment option for patients with obstructive sleep apnea who cannot use conventional therapies.

How similar studies have performed: Previous studies have shown that regular physical activity can significantly reduce the severity of obstructive sleep apnea, indicating a promising avenue for further exploration.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Patient aged 18 to 80 years old

  * Patient with OSA (AHI ≥ 15 events/hr)
  * Patient not receiving any treatment for their OSA
  * Patient able to provide written informed consent
  * Patient able to participate in regular physical activity (no medical contraindication to exercise)

Exclusion Criteria:

* • Pregnancy

  * Person deprived of liberty or subject to a legal protection measure
  * Patient presenting a condition that can influence the results. (According to the investigator's judgment, i.e. heart failure, venous insufficiency).
  * Vulnerable person or legally protected adult.
  * Patients already included in another interventional study
  * BMI \> 30 kg/m²
  * Patient taking diuretics

Where this trial is running

Grenoble

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep Apnea
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.