Impact of Exercise on Blood Sugar Levels During the Menstrual Cycle in Women with Type 1 Diabetes
Effects of the Menstrual Cycle on Blood Glucose Changes During Exercise in Women With Type 1 Diabetes Using Oral Contraceptives
This study is testing how aerobic exercise affects blood sugar levels in women with type 1 diabetes who are on birth control during different phases of their menstrual cycle.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | Female |
| Sponsor | University of Alberta Academic / other |
| Locations | 1 site (Edmonton, Alberta) |
| Trial ID | NCT05188014 on ClinicalTrials.gov |
What this trial studies
This study investigates how aerobic exercise affects glucose levels in women with type 1 diabetes who are using oral contraceptives. Participants will wear continuous glucose monitors during two separate phases of their menstrual cycle: the active pill phase and the placebo phase. They will perform a 45-minute aerobic exercise session at a predetermined intensity, with blood samples taken before, after, and one hour post-exercise to assess glucose response. The study aims to understand the interaction between menstrual cycle phases and exercise on glucose management.
Who should consider this trial
Good fit: Ideal candidates are women with type 1 diabetes who have regular menstrual cycles and are using monophasic oral contraceptives.
Not a fit: Patients with poorly controlled diabetes, significant cardiovascular issues, or contraindications to exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing exercise regimens for better glucose control in women with type 1 diabetes.
How similar studies have performed: While studies on exercise and diabetes exist, this specific focus on menstrual cycle phases in women with type 1 diabetes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * type 1 diabetes diagnosed for at least 1 year * regular menses * using monophasic oral contraceptives * residing in Edmonton, Alberta and able to visit the lab at the University of Alberta Exclusion Criteria: * HbA1c \> 9.9% * frequent and unpredictable hypoglycemia * change in insulin management strategy within two months of the study * use of an automated insulin delivery system * blood pressure \> 140/95 * history of cardiovascular disease * severe peripheral neuropathy * active proliferative retinopathy * use of medications (other than insulin) that would affect blood glucose levels * any musculoskeletal condition that would contraindicate exercise (e.g. sprain, strain, joint injury, etc.)
Where this trial is running
Edmonton, Alberta
- Alberta Diabetes Institute — Edmonton, Alberta, Canada (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.