Impact of exercise during fasting on metabolism and brain function in healthy adults
Efecto De Una Sesión De Ejercicio Físico Realizada Durante Un Periodo De Ayuno De 24-34 Horas Sobre El Metabolismo Energético Y La Función Cognitiva En Adultos Sanos: Estudio Piloto
This study tests how high-intensity exercise during fasting affects energy use and brain function in healthy adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Universidad de Granada Academic / other |
| Locations | 1 site (Granada) |
| Trial ID | NCT05919979 on ClinicalTrials.gov |
What this trial studies
This study investigates how high-intensity exercise affects energy metabolism and cognitive function during a 24-34 hour fasting period in healthy adults. Participants will undergo a randomized crossover design where they will experience both fasting with and without exercise. Measurements will include changes in respiratory exchange ratio, blood substances, and cognitive performance after the fasting periods. The goal is to understand the interaction between fasting and exercise on metabolic and cognitive outcomes.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18-40 with a BMI between 18.5 and 30.0 who have stable body weight.
Not a fit: Patients with chronic conditions affecting energy metabolism or those who cannot safely participate in fasting or high-intensity exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing exercise and fasting for improved metabolic health and cognitive performance.
How similar studies have performed: While the specific combination of fasting and high-intensity exercise is less commonly studied, related research has shown promising results in understanding metabolic responses to exercise and fasting.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-40 years old. * Body mass index: 18.5-30.0 Kg/m2. * Stable body weight (5kg range within the last 3 months) * Being able to consume all the food items provided as part of the study. * Not having change the time zone or have shifted sleeping hours equivalent to more than 3 hours on the previous 2 weeks. Exclusion Criteria: * Diagnosed with any chronic condition that, in the research team's opinion or based on the American College of Sports Medicine guidelines, could contraindicate the implementation of 34-hour fasting periods and/or high-intensity exercise. * Diagnosed with a chronic endocrine, digestive, rheumatic, neurological, cardiac, pulmonary, autoimmune, or infectious condition that affects energy metabolism. * Presenting any signs or symptoms of illness that, in the research team's opinion or based on the American College of Sports Medicine guidelines, could contraindicate the implementation of 34-hour fasting periods and/or high-intensity exercise. * Pregnant or breastfeeding. * Using medications or supplements that may alter energy metabolism. * Currently undergoing or having undergone any type of nutritional intervention or treatment in the past 3 months. * Engaging in more than 5 hours per week of habitual moderate-to-vigorous cycling. * Any other condition that, in the research team's opinion, discourages participation in the study.
Where this trial is running
Granada
- Instiuto Mixto Universitario Deporte y Salud — Granada, Spain (Recruiting)
Study contacts
- Study coordinator: Guillermo Sanchez Delgado, PhD
- Email: gsanchezdelgado@ugr.es
- Phone: +34665186487
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.