Impact of Estrogen Levels on Recovery After IVF Procedures
The Impact of Supraphysiologic Estrogen Levels on Postoperative Recovery Quality in IVF Patients: A Prospective Observational Study
This study is testing how higher estrogen levels affect recovery after IVF procedures in women to see if it makes a difference in how they feel afterward.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Konya City Hospital Academic / other |
| Locations | 1 site (Konya) |
| Trial ID | NCT06925633 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates how elevated serum estrogen levels affect postoperative recovery in women undergoing IVF procedures under general anesthesia. It will include 100 adult female patients aged 18 to 45, assessing recovery quality through the QoR-15 questionnaire and secondary outcomes like pain, nausea, and discharge time. Patients will be categorized based on their estradiol levels, with a focus on those exceeding 350 pg/ml. The study aims to enhance understanding of estrogen's role in recovery dynamics post-anesthesia.
Who should consider this trial
Good fit: Ideal candidates are adult female patients aged 18 to 45, classified as ASA physical status I or II, scheduled for IVF-related oocyte retrieval.
Not a fit: Patients with ASA physical status III or IV, or those with significant comorbidities or psychiatric conditions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative recovery protocols for IVF patients, enhancing their overall experience and outcomes.
How similar studies have performed: While the specific relationship between estrogen levels and postoperative recovery in IVF patients is less explored, related studies have indicated that hormonal levels can influence recovery outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female patients aged between 18 and 45 years * ASA physical status I or II * Scheduled for transvaginal oocyte retrieval under general anesthesia as part of an IVF procedure * Willing and able to provide written informed consent * Able to understand and complete study questionnaires (QoR-15, HADS) Exclusion Criteria: * ASA physical status III or IV * History of severe renal, hepatic, respiratory, or cardiovascular disease * Current or chronic use of psychotropic medications * Chronic use of opioids or benzodiazepines * Known psychiatric or neurological disorders that may interfere with study participation * Inability to provide informed consent or complete study questionnaires
Where this trial is running
Konya
- Konya City Hospital — Konya, Turkey (Recruiting)
Study contacts
- Study coordinator: Mahmut Tutar, MD
- Email: masatı42@gmail.com
- Phone: +905552723704
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.