Impact of enhanced recovery protocols on nausea and vomiting after sleeve gastrectomy

Impact of Enhanced Recovery After Surgery (ERAS) for Sleeve Gastrectomy on Postoperative Nausea and Vomiting: Controlled Randomized Study.

Not applicable Interventional Minia University · NCT05996887

This study tests if following special recovery guidelines can help reduce nausea and vomiting after weight loss surgery for people getting a sleeve gastrectomy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorMinia University Academic / other
Locations1 site (Minya, Minia)
Trial IDNCT05996887 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of enhanced recovery after surgery (ERAS) protocols in reducing postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic sleeve gastrectomy. Patients will be randomly assigned to either a standard care group or an ERAS group, both receiving a combination of antiemetic medications. The study will assess the incidence of PONV and the overall recovery experience of patients following their surgery. The trial aims to provide insights into the benefits of ERAS in improving postoperative outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-60 with a body mass index between 40 and 60 who are scheduled for elective sleeve gastrectomy.

Not a fit: Patients with contraindications to the medications used in the study or those with serious perioperative complications may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce the incidence of postoperative nausea and vomiting, enhancing recovery and patient satisfaction after bariatric surgery.

How similar studies have performed: Previous studies have shown that enhanced recovery protocols can improve postoperative outcomes, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

\* Age: 18-60 years

* Sex: Both sex
* ASA Physical Status: II, III.
* Body mass index: Between 40 and 60 kg/m2.
* Participants: Patients who are undergoing elective Sleeve Gastrectomy

Exclusion Criteria:

* Patients with hypersensitivity or contraindication to haloperidol, dexamethasone, or ondansetron.
* Serious complications in the perioperative period (such as shock, cardiac arrest, hemorrhage, needing transfusion).
* Psychiatric disorder.
* History of migraine.
* Use of opioid, hormonal, anti-inflammatory, and antiemetic medication 24 h prior to surgery.

Where this trial is running

Minya, Minia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nausea and Vomiting, Postoperativesleeve gastrectomynauseavomiting
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.