Impact of Endotracheal Tube Cuff Pressure on Postoperative Sore Throat

Effect of Cuff Pressure of Endotracheal Tube on Postoperative Sore Throat: a Prospective Observational Study

Observational Seoul National University Hospital · NCT05542823

This study tests if keeping the pressure of the breathing tube too high during surgery leads to more sore throats afterward for patients.

Quick facts

Study typeObservational
Enrollment337 (estimated)
Ages19 Years and up
SexAll
SponsorSeoul National University Hospital Academic / other
Locations2 sites (Seoul, Please Select An Option and 1 other locations)
Trial IDNCT05542823 on ClinicalTrials.gov

What this trial studies

This observational study evaluates how the duration of excessive cuff pressure during tracheal intubation affects the incidence of postoperative sore throat in patients undergoing laparoscopic surgery. Continuous monitoring of cuff pressure is conducted to gather data on its correlation with sore throat development post-surgery. Patients are directly questioned about their symptoms to assess the outcomes related to cuff pressure management.

Who should consider this trial

Good fit: Ideal candidates are patients scheduled for laparoscopic surgery requiring endotracheal intubation under general anesthesia.

Not a fit: Patients with pre-existing sore throat or hoarseness, anticipated difficult airways, or those undergoing surgery lasting less than one hour may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved management of cuff pressure during intubation, reducing the incidence of postoperative sore throat.

How similar studies have performed: While the specific approach of monitoring cuff pressure is less commonly studied, similar investigations into postoperative complications related to intubation have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

- Patients undergoing laparoscopic surgery and endotracheal intubation under general anesthesia

Exclusion Criteria:

* Patients who already had sore throat and hoarseness before surgery
* Patients who were expected to have anticipated difficult airway
* Surgery duration \< 1 hour

Where this trial is running

Seoul, Please Select An Option and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Laparoscopic SurgeryTracheal Intubation MorbiditySore-throatLaparoscopic surgeryEndotracheal intubationCuff pressureSore throatHoarseness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.