Impact of Different Surface Treatments on Implant Stability
Clinical Influence of Different Surface Treatments on Implant Stabiity: a Prospective Observational Clinical Study
This study is testing how different treatments for dental implants affect their stability and success in patients needing work on their premolars.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 32 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | International Piezosurgery Academy Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Trieste, TS) |
| Trial ID | NCT06808724 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the primary and secondary stability of dental implants placed in patients requiring rehabilitation in the premolar area, using various surface treatments such as vacuum-plasma activation, ozonated oil, and non-activated implants. The study will measure primary stability through insertion torque and the Implant Stability Quotient (ISQ), while secondary stability will be assessed over 90 days post-implant placement. Additionally, it will monitor implant survival after one year and any complications or adverse events, as well as the relationship between surface treatment and early marginal bone loss at multiple time points.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old requiring implant-supported rehabilitation in the upper premolar or first molar areas with sufficient bone volume.
Not a fit: Patients with uncontrolled medical conditions, recent acute myocardial infarction, or those who are immunocompromised may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the stability and longevity of dental implants, leading to improved rehabilitation outcomes for patients.
How similar studies have performed: Previous studies have explored various surface treatments for dental implants, showing promising results, but this specific approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age older than 18 years old; * Indication for an implant-supported rehabilitation in the left and right upper premolar/first molar areas; * The area in which the implants will be placed must have had at least 6 months of healing; * No use of grafts or bone substitutes following tooth extraction; * Bone volume measuring at least 10 mm in height and 6 mm in width; * Absence or decision to not wear a removable prosthesis during the healing period; * Patients with good and stable oral hygiene; * Signed informed consent form. Exclusion Criteria: * Acute myocardial infarction within the previous six months; * Uncontrolled bleeding disorders; * Uncontrolled diabetes (HBA1c \> 7.5%); * Radiotherapy in the head-neck area in the previous 48 months; * Immunocompromised patients (es. AIDS / chemotherapy); * Current or previous treatment with antiresorptive drugs via intravenous injection; * Psychological or psychiatric disease; * Alcohol and /or drugs abuse; * Heavy smokers (more than 10 cigarettes / day); * Plaque index \>20% and/or bleeding on probing \>10% * Pregnant or breastfeeding patients; * Patients refusing to participate in follow-up checks.
Where this trial is running
Trieste, TS
- University of Trieste — Trieste, Ts, Italy (Recruiting)
Study contacts
- Study coordinator: Claudio Stacchi, Dott.
- Email: claudio@stacchi.it
- Phone: +39 0403992254
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.