Impact of different omega-3 oil supplements on health in healthy adults
A Randomized Controlled Clinical Trial Assessing the Impact of 14-week Natural Salmon Oil Supplementation (CARDIO®) on the Omega-3 Index Response and Cardiometabolic and Inflammatory Biomarkers in Healthy, Non-Pregnant Adults
This study is testing whether two types of omega-3 oil supplements can improve heart health and other health markers in healthy adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 96 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | Hofseth Biocare ASA Industry-sponsored |
| Locations | 2 sites (Menlo Park, California and 1 other locations) |
| Trial ID | NCT06802068 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of two types of omega-3 oil supplements—a whole, unprocessed salmon oil and a standard, processed omega-3 oil—on the omega-3 index and various markers of cardiometabolic health in healthy adults. It aims to determine whether these supplements can effectively improve inflammation, oxidative stress, cholesterol levels, and diabetes risk. Additionally, the study will assess changes in sleep metrics using questionnaires and wearable devices. Participants will be monitored over a specified period to measure these health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy, non-pregnant adults aged 40-80 years with stable body weight.
Not a fit: Patients with fish or seafood allergies, those already taking fish oil supplements, or individuals with certain health conditions like diabetes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective omega-3 supplementation strategies that enhance cardiometabolic health.
How similar studies have performed: While there have been studies on omega-3 supplementation, this specific comparison of whole salmon oil versus processed omega-3 oil is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy, non-pregnant adults; 40-80 years of age; stable body weight prior 3 months Exclusion Criteria: * Fish or seafood allergies; Pregnant; already consuming fish oil supplementation; malabsorption states; malignancy in remission for less than 12 months; diabetic
Where this trial is running
Menlo Park, California and 1 other locations
- Alethios — Menlo Park, California, United States (Recruiting)
- Alethios, Inc. — San Francisco, California, United States (Recruiting)
Study contacts
- Principal investigator: Crawford Currie, MBBS — Hbc
- Study coordinator: Crawford Currie, MBBS
- Email: cc@hofsethbiocare.no
- Phone: 1-650-206-8006
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.