Impact of diaphragm weakness in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the incidence and prognostic impact of diaphragm dysfunction in patients discharged from the ICU. It involves assessing diaphragmatic function using ultrasound within 24 hours after weaning from ventilatory support and on the day of ICU discharge. The study aims to correlate diaphragmatic activity with patient outcomes, specifically looking at the relationship between diaphragmatic dysfunction and prognosis within 90 days post-discharge. Dyspnea will also be measured to provide a comprehensive evaluation of respiratory muscle function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years
2. Invasive or non-invasive respiratory support (ventilation, high-flow oxygen therapy, whatever the reason) for at least 48 hours.
3. Weaning from respiratory support (invasive or not) within the last 24 hours.
4. Patient (or trusted person/relative) informed and not opposed to the study.

Exclusion Criteria:

1. Known pre-existing diaphragmatic dysfunction (phrenic lesion, neuromuscular disease, etc.)
2. Patients with tracheostomy
3. Non-communicating patients
4. Patients deprived of liberty by court or administrative order, or under legal protection (guardianship, curators).

Where it's running

• Médecine intensive Réanimation
  Paris, France Recruiting

Study contacts

• Study coordinator: Martin Dres, MD,PHD
• Email: martin.dres@aphp.fr
• Phone: 0142167809

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.