Impact of Deep Neuromuscular Block on Recovery After Laparoscopic Hysterectomy
Effect of Deep Neuromuscular Block on the Quality of Recovery After Laparoscopic Hysterectomy
This study tests if using a deeper level of muscle relaxation during laparoscopic hysterectomy helps women recover better compared to a moderate level of relaxation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Anqing Municipal Hospital Academic / other |
| Locations | 1 site (Anqing, Anhui) |
| Trial ID | NCT06469866 on ClinicalTrials.gov |
What this trial studies
This study investigates whether deep neuromuscular blockade (NMB) improves recovery quality after laparoscopic hysterectomy compared to moderate NMB. Seventy-two women undergoing elective laparoscopic hysterectomy are randomly assigned to receive either low-pressure pneumoperitoneum with deep NMB or standard-pressure pneumoperitoneum with moderate NMB. The primary outcome measured is the quality of recovery one day post-surgery, while secondary outcomes include postoperative pain levels, surgical conditions, and other recovery metrics.
Who should consider this trial
Good fit: Ideal candidates are women scheduled for elective laparoscopic hysterectomy with an ASA physical status of I to III.
Not a fit: Patients with a BMI over 35, renal or hepatic insufficiency, or neuromuscular diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance recovery quality and reduce postoperative pain for patients undergoing laparoscopic hysterectomy.
How similar studies have performed: Previous studies have suggested that deep neuromuscular blockade may improve surgical conditions and postoperative outcomes, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status Ⅰ- Ⅲ * Scheduled for elective laparoscopic hysterectomy Exclusion Criteria: * Inability to give informed consent * BMI \>35 * Renal or hepatic insufficiency * History of preoperative psychiatric * Previous surgery at procedure site * Neuromuscular disease, pregnancy, and contraindications to study medications.
Where this trial is running
Anqing, Anhui
- Department of Anqing Munucipal Hospital Anesthesiology — Anqing, Anhui, China (Recruiting)
Study contacts
- Study coordinator: Xu si qi, Doctor
- Email: errtg555@163.com
- Phone: 13865192106
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.