Impact of Cryolipolysis on Insulin Resistance in Obese Individuals

Effect of Cryolipolysis on Insulin Resistance in Type 2 Diabetic Females With Abdominal Obesity

Not applicable Interventional Cairo University · NCT06223490

This study is testing if a fat-freezing treatment can help obese women with type 2 diabetes improve their insulin sensitivity and blood sugar levels.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages35 Years to 45 Years
SexFemale
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06223490 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of cryolipolysis, a non-invasive fat reduction technique, on insulin resistance in obese females diagnosed with type 2 diabetes mellitus. Participants will undergo cryolipolysis treatment while being monitored for changes in their insulin sensitivity and blood glucose levels. The study aims to determine whether this intervention can improve metabolic outcomes in individuals struggling with obesity and diabetes. Eligible participants will be between the ages of 35 and 45, with specific inclusion criteria related to their diabetes management and body mass index.

Who should consider this trial

Good fit: Ideal candidates for this study are obese females aged 35 to 45 with a diagnosis of type 2 diabetes and fasting glucose levels above 140 mg/dL.

Not a fit: Patients who are insulin-dependent, have renal failure, cardiovascular issues, or other significant health problems may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide a novel approach to improving insulin sensitivity and managing type 2 diabetes in obese patients.

How similar studies have performed: While the use of cryolipolysis for fat reduction is established, its specific effects on insulin resistance in diabetic patients are novel and have not been extensively tested in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with incidence of diabetes 5 years ago.
* Patient fasting glucose level is more than 140 mg/dL.
* Age will be ranged from 35 to 45 years
* Body mass index between 25 and 30.
* All patients are medically controlled
* All patients have the same medical care.
* All patients will receive a good explanation of treatment procedures.

Exclusion Criteria:

* Patients dependent on insulin.
* Renal failure.
* Myocardial infractions.
* Cardiovascular problems.
* Neurological disorders.
* Patients with orthopedic problems (e.g mal or incomplete union of fracture, ankle sprains.
* Abdominal hernia
* Skin disease
* Unstable cases

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Type 2 Diabetes Mellitus in ObeseCryotherapy EffectTII DMObese FemalesCryolipolysis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.