Clinical trial Recruiting at 1 site Observational Ages 18 and up

Impact of comorbidities after radical cystectomy using an AI-based predictive method

Official title: Evaluation of the Impact of COMORBIDities on Morbidity and Mortality After Radical Cystectomy for Cancer Using a Predictive Method With Artificial Intelligence

Run by Centre Hospitalier Universitaire, Amiens · NCT05204186 · Data updated 2026-11-12

This study tests whether an AI-based method can help predict outcomes for bladder cancer patients undergoing radical cystectomy, focusing on how comorbidities influence treatment choices and survival.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens, Picardie)
StatusRecruiting
StartedAugust 12, 2021
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedJune 15, 2026
Trial IDNCT05204186 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older who have undergone radical cystectomy for bladder cancer.

Probably not a fit

Patients without sufficient data on comorbidities or with distant metastases at baseline may derive limited or no benefit from the predictive approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses a predictive approach that combines artificial intelligence and clinical data to understand how non-cancer health conditions affect decisions at the urologic oncology team and patient outcomes after radical cystectomy for bladder cancer. The project aims to quantify how comorbidities and provider judgment influence guideline adherence and survival, using methods like cumulative incidence to account for competing mortality risks. Data are analyzed to identify patients at higher risk of early death and to inform more tailored treatment guidelines. The study is centered at CHU Amiens with collaboration from local oncology teams, evaluating real-world practice patterns and outcomes.

Why it matters

Potential benefit: If successful, the approach could improve risk stratification and guide more personalized treatment decisions for bladder cancer patients undergoing surgery.

How similar studies have gone: Previous work with AI and comorbidity data in urologic oncology has shown promise, but this exact predictive method in radical cystectomy care is an emerging area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years and older
* Patient treated by radical cystectomy for bladder cancer

Exclusion Criteria:

* Computed tomography/magnetic resonance evidence of distant metastases.

Where it's running

  • CHU Amiens Picardie
    Amiens, Picardie, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.