Impact of Chair Yoga on Heart Health and Metabolism
The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease
This study is testing whether a 16-week chair yoga program can improve heart health and metabolism in people with coronary artery disease compared to standard care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Icahn School of Medicine at Mount Sinai Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT05250310 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of a 16-week chair yoga program on micro RNA expression and cardiovascular disease risk factors in patients with coronary artery disease. It involves 120 participants who will be randomized into two groups: one practicing chair yoga and the other receiving standard care. The study aims to determine how yoga influences metabolic processes related to cardiovascular health by analyzing blood samples for miRNA expression before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-80 who have undergone percutaneous coronary intervention or have non-obstructive coronary artery disease with at least one cardiovascular risk factor.
Not a fit: Patients without any cardiovascular disease risk factors or those who are not eligible based on the inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a non-invasive lifestyle intervention to improve cardiovascular health and metabolic processes in patients with coronary artery disease.
How similar studies have performed: Previous studies have shown that yoga can effectively improve cardiovascular risk factors, suggesting that this approach may yield positive results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Subjects eligible for the study are 18-80 year old adults. * Underwent percutaneous coronary intervention (PCI) at the catheterization lab of Mount Sinai Hospital (New York, New York) or have non-obstructive coronary artery disease and at least one CVD risk factor (hypertension, hypercholesterolemia, diabetes mellitus, or obesity) or metabolic abnormality (fasting plasma glucose ≥ 100 mg/dl, documented previous diagnosis of hypertension, serum triglycerides ≥ 150 mg/dl, or HDL cholesterol \< 40 mg/dl). * Subjects diagnosed with metabolic syndrome, which is defined as three or more of the following conditions: (1) Central or abdominal obesity (waist circumference \> 40 inches for men and \> 35 inches for women); (2) High triglycerides (≥150 mg/dL or triglycerides treatment); (3) Low HDL cholesterol (\<40 mg/dL for men and \<50 mg/dL for women) or low HDL-C treatment; (4) High blood pressure (≥130/85 mmHg) or antihypertensive medications; (5) High fasting glucose (≥100 mg/dL) or type 2 diabetes mellitus. * Participants must be able to willingly consent to study participation and must be able to comply with the study requirements. Exclusion Criteria: * Physical/psychological limitation or unwillingness to practice yoga, * Congestive heart failure, known arrthymias or prior Automated Implantable Cardioverter-Defibrillator /pacemaker or any metallic implants, * Rheumatological/immunological diseases, * History of transplant, * Moderate to severe chronic obstructive pulmonary disease, debilitating or severe systemic Illness, * Subjects who are pregnant or postpartum less than 6 months, * Liver disease or alcohol use of more than 7 alcoholic drinks/week in women and more than 14 drinks/week in men
Where this trial is running
New York, New York
- Mount Sinai Hospital — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Annapoorna Kini, MD — Mount Sinai Hospital
- Study coordinator: Yuliya Vengrenyuk
- Email: yuliya.vengrenyuk@mountsinai.org
- Phone: 212-241-0460
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.