Impact of Caesarean Section Scars on IVF Outcomes
CS Scar Impact on ART Outcomes
This study is trying to see if having scars from previous C-sections affects the success of IVF treatments in women aged 25-40.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 510 (estimated) |
| Ages | 25 Years to 40 Years |
| Sex | Female |
| Sponsor | HealthPlus Fertility Center Academic / other |
| Locations | 1 site (Abu Dhabi) |
| Trial ID | NCT06021886 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how the presence of caesarean section scars, with or without defects, affects the outcomes of assisted reproductive technology (ART), specifically in vitro fertilization (IVF). It is a retrospective cohort study that compares pregnancy success rates following frozen embryo transfers of euploid embryos in women with and without caesarean section scars. The study aims to identify factors such as embryo transfer difficulties and intrauterine fluid presence that may influence implantation rates and miscarriage risks. Women aged 25-40 who underwent embryo transfers between 2015 and 2022 will be included if they meet specific medical criteria.
Who should consider this trial
Good fit: Ideal candidates are women aged 25-40 who are undergoing frozen embryo transfer with euploid embryos and have a BMI less than 30.
Not a fit: Patients with previous uterine scars other than caesarean sections or those with congenital uterine abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights that improve IVF outcomes for women with caesarean section scars.
How similar studies have performed: While there is limited data on this specific approach, similar studies have explored the impact of uterine conditions on IVF outcomes, suggesting potential relevance.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 25-40 years old. Euploid embryo transfer. Medically free BMI less tha 30 kg/m2 Hormone therapy preparation for FET. Exclusion Criteria: - Exclusion criteria Previous uterine scar other than cesarean section. Congenital uterine abnormalities Presence of intrauterine lesions e.g., polyp, fibroid, Endometriosis or adenomyosis Hydrosalpinx, Chronic endometritis
Where this trial is running
Abu Dhabi
- HealthPlus fertility Centre — Abu Dhabi, United Arab Emirates (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.