Impact of booster sessions on depression vulnerability after cognitive control training
Evaluating the Effects of Personalized Booster Sessions on Depression Vulnerability Following Cognitive Control Training for Remitted Depressed Individuals
This study is testing if extra booster sessions of cognitive control training can help people who are in remission from major depression stay healthy and avoid a relapse.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 138 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University Ghent Academic / other |
| Locations | 2 sites (Ghent, Oost-Vlaanderen and 1 other locations) |
| Trial ID | NCT05557760 on ClinicalTrials.gov |
What this trial studies
This study investigates how booster sessions of cognitive control training (CCT) affect depression vulnerability in individuals who are in remission from major depression. Participants will be randomly assigned to two groups, both receiving 10 sessions of the adaptive Paced Auditory Serial Addition Task, a recognized CCT method. One group will receive additional booster sessions based on early warning signs of potential depression recurrence, while the other group will not. The study will monitor participants' functioning weekly over a 15-week period to assess the effectiveness of these booster sessions.
Who should consider this trial
Good fit: Ideal candidates are individuals with a history of at least one depressive episode who are currently in remission for at least three months.
Not a fit: Patients currently experiencing a depressive episode or those with psychotic disorders or significant neurological impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance long-term resilience against depression relapse for individuals in remission.
How similar studies have performed: Previous studies have shown promising results for cognitive control training in preventing depression recurrence, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * History of ≥ 1 depressive episode(s) * Currently in remission (≥ 3 months) * Access to a computer with an internet connection * Access to a smartphone Exclusion Criteria: * Ongoing depressive episode * Psychotic disorder (current and/or previous) * Neurological impairments (current and/or previous) * Excessive substance abuse (current and/or previous) * Use of antidepressant medication is allowed if kept at a constant level
Where this trial is running
Ghent, Oost-Vlaanderen and 1 other locations
- Ghent University Hospital — Ghent, Oost-Vlaanderen, Belgium (Not_yet_recruiting)
- Ghent University — Ghent, Oost-Vlaanderen, Belgium (Recruiting)
Study contacts
- Study coordinator: Ernst Koster, PhD
- Email: Ernst.Koster@ugent.be
- Phone: + 32 9 2646446
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.