Impact of body posture on airway protection in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how forward trunk flexion in patients with Parkinson's disease affects their respiratory muscle strength and voluntary cough. It aims to establish a relationship between postural abnormalities and the deterioration of these respiratory functions over a three-year period. Additionally, the study will explore correlations between respiratory muscle strength, voluntary cough strength, handgrip strength, and pulmonary dysfunction index as potential screening methods for assessing airway defense mechanisms in these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Parkinson' s disease
* Age ≥ 18 years

Exclusion Criteria:

* Unreliable performance of MIP, MEP, or grip strength measurements, for example, due to cognitive deficits (assessed by the researcher)
* Inadequate lip seal
* Significant deformities of the dominant hand that could affect the accuracy of grip strength measurements
* Other severe neurological diseases apart from PD
* History of unstable cardiovascular disease
* Severe pulmonary disease

Where it's running

• General University Hospital
  Prague, Czechia Recruiting

Study contacts

• Study coordinator: Kateřina Dvořáková, MSc.
• Email: katerina.dvorakova@vfn.cz
• Phone: +420 224 965 513

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.