Impact of Aplastic Anemia on Reproductive and Mental Health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with aplastic anemia (AA) to assess the effects of the disease and its treatments on reproductive health and mental well-being. It aims to monitor sex hormone levels in male and female patients aged 18-40 years, as reproductive health issues such as irregular menstruation and infertility are common among this population. The study will evaluate how treatments like immunosuppressive therapy may contribute to reproductive impairments. By understanding these impacts, the study seeks to provide insights into the overall health challenges faced by AA patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of AA
* Male or female, aged 18-40 years
* ECOG performance status ≤2
* Willing and able to comply with the requirements for this study and written informed consent

Exclusion Criteria:

* Diagnosis of inherited bone marrow failure syndromes
* Combined with other hematological diseases
* Chemotherapy-induced bone marrow failure
* Pregnant or breastfeeding women
* Subjects with a history of mental illness or severe psychological disorders
* Subjects with a history of reproductive system cancer (eg, penile cancer, testicular cancer, prostate cancer, ovarian cancer, cervical cancer, vaginal cancer, etc.)
* Subjects that the investigator believes have other reasons that make them unsuitable for inclusion in this study

Where it's running

• Regenerative Medicine Center
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Jingyu Zhao, MPH
• Email: zhaojingyu@ihcams.ac.cn
• Phone: 13752253515

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.