Impact of alcohol consumption on dental anesthesia success rates
Effect of Alcohol Consumption on the Success Rates of Local Anesthesia in Patients With Symptomatic Irreversible Pulpitis
This study is testing how drinking alcohol affects the effectiveness of dental anesthesia in people with severe tooth pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | Jamia Millia Islamia Academic / other |
| Locations | 1 site (New Delhi) |
| Trial ID | NCT06201871 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how alcohol consumption affects the success of local anesthesia in patients with symptomatic irreversible pulpitis. Seventy adult participants, divided into two groups of alcoholics and non-alcoholics, will receive an inferior alveolar nerve block (IANB) using 2% lidocaine. Pain levels during the procedure will be assessed using the Heft-Parker scale, with a successful injection defined as a pain score below 55. The study aims to provide insights into the relationship between alcohol use and pain management in dental procedures.
Who should consider this trial
Good fit: Ideal candidates include adults with symptomatic irreversible pulpitis in mandibular molars, categorized as either low-moderate alcohol consumers or non-drinkers.
Not a fit: Patients with multiple active dental issues or significant medical contraindications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve pain management strategies for dental patients with varying alcohol consumption habits.
How similar studies have performed: While there is limited research specifically on alcohol's impact on dental anesthesia, studies on alcohol's effects on pain perception suggest this approach could yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Symptomatic carious exposed mandibular first or second molars. * Alcoholic patients: Patient with low-moderate drinking levels according to the US National Institute on Alcohol Abuse and Alcoholism * Control patients: No history of alcohol consumption * Positive and prolonged response to thermal sensitivity tests and electric pulp test. * Vital coronal pulp on access cavity preparation. * American Society of Anesthesiologists class I or II medical history. * Ability to understand the use of pain scales. Exclusion Criteria: * Active pain in more than 1 teeth * Teeth with fused roots. * Radiographic evidence of an extra root. * Large restorations with overhanging margins. * Full crowns or deep periodontal pockets. * Hypertension or cardiovascular diseases, compromised immunity, active infection or inflammation * Known allergy or contraindications to any content of the local anesthetic solution or non-steroidal anti-inflammatory drugs (NSAIDs) * History of known or suspected drug abuse. * Taking any drugs which could affect the pain perception, e.g, opioids, antidepressants, anticonvulsants, muscle relaxants, anxiolytics, sedatives, nsaids. 23 * Pregnant or breastfeeding patients. * Patients with asthma, gastric ulcers, bleeding disorders.
Where this trial is running
New Delhi
- Faculty of Dentistry, Jamia MIliia Islamia — New Delhi, India (Recruiting)
Study contacts
- Study coordinator: Vivek Aggarwal
- Email: drvivekaggarwal@gmail.com
- Phone: 9818188358
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.