Impact of activity levels on preterm delivery risk in women with a short cervix
The Effect of Routine Activity on the Risk for Preterm Delivery in Women With a Short Cervix. A Randomized Control Trial
This study is testing if staying active instead of resting a lot can help pregnant women with a short cervix avoid having their babies too early.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Sex | Female |
| Sponsor | Wolfson Medical Center Government |
| Locations | 1 site (Holon) |
| Trial ID | NCT06884761 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effects of routine physical activity compared to strict bed rest on the risk of preterm delivery in pregnant women diagnosed with a short cervix between 24 and 34 weeks of gestation. Participants will be randomized into two groups: one group will maintain their usual activity levels while the other will be advised to rest maximally. The study aims to determine if routine activity influences gestational age at delivery and secondary outcomes such as preterm labor and maternal anxiety. Participants will wear a smart band to monitor their activity levels over a two-week period and will have regular follow-ups at a high-risk pregnancy clinic.
Who should consider this trial
Good fit: Ideal candidates are pregnant women with singleton pregnancies between 24 and 34 weeks who have a cervical length of less than 25 mm.
Not a fit: Patients with twin pregnancies, medical contraindications to physical activity, or other serious maternal or fetal complications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide evidence that routine activity may reduce the risk of preterm delivery in women with a short cervix.
How similar studies have performed: While there have been studies on activity levels during pregnancy, this specific approach focusing on women with a short cervix is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Singleton pregnancies between 24+0 and 34+6 weeks. * Short cervical length (\<25 mm) confirmed via transvaginal ultrasound. * No medical contraindications to physical activity. Exclusion Criteria: * Twin pregnancies or higher-order multiples. * Medical indications for reduced mobility (e.g., symphysiolysis, fall risk). * Maternal comorbidities, fetal distress, vaginal bleeding, PPROM, or need for immediate delivery.
Where this trial is running
Holon
- The Edith Wolfson Medical Center — Holon, Israel (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.