Impact of Abutment Design on Tissue Around Dental Implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of different abutment configurations on the hard and soft tissue around dental implants placed in the aesthetic zone of the maxilla. Patients with a single missing tooth will receive either custom or cylindrical healing abutments, followed by screw-retained ceramic crowns. The study will measure tissue volume changes, keratinized mucosa thickness, and blood flow during the healing process. Outcomes will be assessed using aesthetic scores and monitoring for complications over a three-year period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients over 18 years
* good general health
* good oral hygiene (FMPS \< 25%)
* healthy periodontium (PPD \< 4mm)
* thick phenotype
* maxilla anterior region (extended to 15-25 positions)
* solo missing teeth, intact adjacent teeth
* type 1 alveolar shape after extraction 1
* retained occlusion
* baseline buccal bone wall thickness at least 1.5 mm, based on intact CBCT scan
* patient voluntarily accepts and signs the information and consent form for the study

Exclusion Criteria:

* general ill health
* general surgical or oral surgery contraindication
* a patient who has undergone local radiotherapy
* active periodontal inflammation, inflammation of the alveolar cavity
* smoking
* posterior region
* pregnancy, lactation
* psychological or mental involvement affecting individual plaque control
* presence of an implant adjacent to the planned implant
* inadequate oral hygiene
* need for vertical bone augmentation
* gingival recession
* Inappropriate implant position for screw fixation
* bruxism

Where it's running

• Semmelweis University, Department of Prosthodontics
  Budapest, Pest County, Hungary Recruiting

Study contacts

• Principal investigator: Krisztina Mikulás, PhD — Semmelweis University, Department of Prosthodontics
• Study coordinator: Krisztina Mikulás, PhD
• Email: mikulas.krisztina1@semmelweis.hu
• Phone: +36309365144

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery

  Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.

  Recruiting Semmelweis University · Budapest · NCT07896174

• How jaw surgeries affect the jaw joint, using a movement device

  This study tests how orthognathic surgery changes jaw joint movement in adults with severe dentofacial deformities.

  Recruiting Semmelweis University · Budapest · NCT07828041

• AI into Ultrasound Diagnostics in Reproductive Medicine

  Researchers are testing AI tools that analyze transvaginal ultrasound images to help detect endometriosis, adenomyosis, uterine masses, and pregnancy-related receptivity in women aged 18-45.

  Recruiting Semmelweis University · Budapest, Budapest · NCT07810920

• Virtual nature vs guided imagery for anxiety and well-being in hospitalized older adults

  In this study, hospitalized adults 65 and older try two ways to bring nature to them: watching 360-degree nature videos on a VR headset or listening to a guided imagery audio to imagine the same scenes, to see which helps mood and anxiety during a two-week period.

  Recruiting at 2 sites Semmelweis University · Budapest and 1 other locations · NCT07765355

• Topical Cyclosporine 1% for Severe Pediatric Ocular Surface Inflammation

  This study tests whether daily topical Cyclosporine 1% helps children with severe allergic eye inflammation and if it reduces the need for rescue steroids.

  Recruiting Semmelweis University · Budapest, Pest County · NCT07732855

• Using DIMS Glasses to See if Myopia Progression Slows in Kids

  This observational study tests whether wearing DIMS glasses in children and teens with myopia can slow progression, considering factors like outdoor time and family history.

  Recruiting Semmelweis University · Budapest · NCT07698977

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.